Protein Info for CA265_RS21625 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1194 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details transmembrane" amino acids 177 to 198 (22 residues), see Phobius details PF05227: CHASE3" amino acids 38 to 170 (133 residues), 93.5 bits, see alignment E=3.9e-30 PF00672: HAMP" amino acids 226 to 268 (43 residues), 26.2 bits, see alignment (E = 2.9e-09) PF13185: GAF_2" amino acids 300 to 428 (129 residues), 53.1 bits, see alignment E=1.4e-17 PF01590: GAF" amino acids 300 to 428 (129 residues), 24.1 bits, see alignment E=1.6e-08 PF00512: HisKA" amino acids 528 to 593 (66 residues), 68.4 bits, see alignment 1.6e-22 PF02518: HATPase_c" amino acids 641 to 752 (112 residues), 100.2 bits, see alignment E=3.4e-32 PF00072: Response_reg" amino acids 804 to 911 (108 residues), 51 bits, see alignment E=5.3e-17 amino acids 926 to 1028 (103 residues), 36.7 bits, see alignment E=1.5e-12 amino acids 1071 to 1183 (113 residues), 97.8 bits, see alignment E=1.5e-31

Best Hits

Predicted SEED Role

"Signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9ZAY2 at UniProt or InterPro

Protein Sequence (1194 amino acids)

>CA265_RS21625 histidine kinase (Pedobacter sp. GW460-11-11-14-LB5)
MKTTLKNNLRLGLGLSLIILFISSLASYISINNLIKSTELVKHSDEVILNSESIISYLKD
AETGQRGFLLTGNKVFLTPYYGASDSAAVILKRVELDTKDNSVQQKNVAALKSILFKRMD
IIKSTIEIKTLGGVIDPTVLFQGKVYMDEARSIVSKMVIEEKRLLEERTNELNKLTAYTP
ILILIAALLAILITLFFYRRVSIDFDERVKLQQEIEDKKYEMEKRIVAIKEIAYQISNGN
YGVKLDSQSRDDIGELADSLNTMSTSLKKSFDTLEENEWLQTGVANLNVKMVGEKDVFHL
AEDIIAFLANYTRSQIGAIYLFKDDGYLHLKGQYALQGQNLAQTIELGQGLIGQSVKTGK
PIFLDDVPQNELTVTHATGNIKPAQLIVLPIIRNEISIGGLELGTIGKYSDLQLHFLNLV
LSDVGTALLGAQNRQKLQQLLEETQAQSEELQVQHNELEGLNAELEAQAQKLQASEEELR
VQQEELLQSNQELEERSSLLEEKNELIEERNIEIQQKAEALELSTRYKSEFLANMSHELR
TPLNSILLLSRLMAENEAMDREHQEYAEVIQSSGQGLLSLIDEILDLSKIEAGKMELDRT
NIKVDEIIFNMRSLFNPLAKEKNLNFVIEKSAEVPEFFHTDKMRLEQIIKNLLSNAIKFT
TVGAVTLNINKNEKLGALVFKVTDTGVGIAPEKQGMVFEAFQQADGSTRRKFGGTGLGLS
ISRELAKLLGGYIDLKSTEGEGSIFTLTLPIDRNKGFDGVVPSADKPVIALEPPVKKVSH
LTVENIPQEIEDDRDNIQPDDKVILIVEDDTPFAKTLLDFTRKRNYKGLVAVRGDAGIEM
AKTFKPLAILLDIQLPVKDGWQVMEELKSDPSTRPIPVHIMSSLQVKKESLLKGAVDFIN
KPFAFEHMQEIFSKLEHALSRHPKKVLIVEENEQHAKALSYFLSNFNIQTEIVNQVNESV
SALHKPEVNCVILDMGIPDKHAYETLEVVKKTPGLENLPIIIFTGKNLSKGEENRIKQYA
DSIVVKTAHSYQRILDEAGLFLHLVEEKSKEKTKTPKKFSELQDVLVGKTVLVADDDVRN
IFSLTKMLEQHQMKVVAATDGKEALKLLNENPEIDVVLMDMMMPELDGYETTTAIRQDIK
YRNLPILAVTAKAMMGDREKCIAAGASDYISKPVDMDQLISLLRVWLYENHHKS