Protein Info for CA265_RS20860 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: oligopeptidase B

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 716 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details PF02897: Peptidase_S9_N" amino acids 43 to 439 (397 residues), 348.1 bits, see alignment E=6.3e-108 PF00326: Peptidase_S9" amino acids 499 to 709 (211 residues), 219.2 bits, see alignment E=4.6e-69

Best Hits

Swiss-Prot: 46% identical to PTRB_ECOLI: Protease 2 (ptrB) from Escherichia coli (strain K12)

KEGG orthology group: K01354, oligopeptidase B [EC: 3.4.21.83] (inferred from 72% identity to shg:Sph21_1246)

MetaCyc: 46% identical to oligopeptidase B (Escherichia coli K-12 substr. MG1655)
Oligopeptidase B. [EC: 3.4.21.83]

Predicted SEED Role

"Protease II (EC 3.4.21.83)" (EC 3.4.21.83)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.21.83

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9ZAB9 at UniProt or InterPro

Protein Sequence (716 amino acids)

>CA265_RS20860 oligopeptidase B (Pedobacter sp. GW460-11-11-14-LB5)
MKRILPGLIVLSAITACNNPQKKEMKAIKWPDAKAPVAEIIPHQRVIHGDTVVDNYYWMI
DYFKKGPDSTKVVDYLKAENTYLNTMMKSTDQFQADLFKEMKGRIKEKDESVPVFKNGYF
YYTRTEDGQQYFKYCRKKGSLSAAEEILLDVDKLAKGHAYYSATGFNVSPDNKLLAFGVD
QVSRRQYTINVKNLETGEILKDAITNTEGGVAWANDNKTLFYTSKNPVTLLSEKIKKHTL
GTDAKTDVVVYDEKDNSNYIGVMKSKNGRFIFIASQGTLTTEYRMIDADHPEAAFKVFSP
RSNDVLYDILTVDDKFYIVTNWNAKNFRLMQCPLDKTEKENWKEVIPNRKDVLLEYGEEF
KDHLVLSERKNGLTELRVLKKDGSDYYIKFDEPVYAAGVGANPEYNSKTLRYSYTSLTTP
NSVYDYDLEKKDKKLMKQQEVVGGYDPKDYATERVFATAKDGTKIPIALVYKKGFKKNSN
APLLLYAYGSYGSSTDANFSSPRLSLLNRGFVFAIANIRGGQEMGRQWYEDGKLMKKKNT
FTDFISAGEYLVDQKYTSKGHLYAHGGSAGGLLMGAVANMAPDLWNGIIADVPFVDVINT
MLDESIPLTTNEFDEWGNPKQKAAYDYMKSYSPYENVEKKAYPNMLVTTGLHDSQVQYFE
PAKWVAKLRATKTDKNVLLLKTNMEFGHGGASGRFDYLKDVSLRWAFLFSLEGITK