Protein Info for CA265_RS20480 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: restriction endonuclease subunit S

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 465 PF12161: HsdM_N" amino acids 3 to 41 (39 residues), 27.7 bits, see alignment 4e-10 PF02384: N6_Mtase" amino acids 113 to 420 (308 residues), 202.1 bits, see alignment E=1.4e-63

Best Hits

Predicted SEED Role

"Type I restriction-modification system, DNA-methyltransferase subunit M (EC 2.1.1.72)" in subsystem Restriction-Modification System (EC 2.1.1.72)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.72

Use Curated BLAST to search for 2.1.1.72

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9ZAI7 at UniProt or InterPro

Protein Sequence (465 amino acids)

>CA265_RS20480 restriction endonuclease subunit S (Pedobacter sp. GW460-11-11-14-LB5)
MDLVNKLWNFCHTLRHEGVDYNDYIEELTYLLFLKLAEEIDTKIPDGCDWATLIQSPDSD
LLSNYNSILRELSNQSGILKDIFSEPIAKIHNSSSLRKLLNLIDEINWHSYNQDVLGATF
EGLLERAANESKKGAGQYFTPRPLIQAIVKVMKPDPFESPNFKISDIACGTAGFLTESFA
WWKSSNEINKLTNFQREKLVNNTYIGQELVIRPRRLALMNMYLHGLEPTIILGDTIYEPI
PINEITCSCLLTNPPFGTKGSNQIPDRDFAIKTSNKQLNFIQHAYEILEPSGRAAIVLPD
SVLFEDKATELWEYLMKNVNIHTILKLPLGTFSPYAQGVKANVIFFQKNAITEQVWIYDA
RTNIPGITKKDRPLSPFHFEDFENCYGDDPNGKGVRLETERFKKFDIKNIEERNFNLNIS
WINPNTDESNNHLAPDDLLSEAIAETESLLEELKSIFDSLESNDK