Protein Info for CA265_RS20000 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: sigma-54-dependent Fis family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 469 PF00072: Response_reg" amino acids 5 to 114 (110 residues), 92.9 bits, see alignment E=5.1e-30 PF00158: Sigma54_activat" amino acids 148 to 313 (166 residues), 206.9 bits, see alignment E=6.1e-65 PF14532: Sigma54_activ_2" amino acids 148 to 317 (170 residues), 68.9 bits, see alignment E=1.9e-22 PF00004: AAA" amino acids 170 to 288 (119 residues), 23.9 bits, see alignment E=1.7e-08 PF07728: AAA_5" amino acids 170 to 294 (125 residues), 28 bits, see alignment E=7e-10 PF02954: HTH_8" amino acids 426 to 462 (37 residues), 40.1 bits, see alignment 8.8e-14

Best Hits

KEGG orthology group: None (inferred from 68% identity to phe:Phep_4238)

Predicted SEED Role

"rteB, two-component system response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9ZA96 at UniProt or InterPro

Protein Sequence (469 amino acids)

>CA265_RS20000 sigma-54-dependent Fis family transcriptional regulator (Pedobacter sp. GW460-11-11-14-LB5)
MKNKILIIDDEINIGLLLSKFLTKSGFDVLHTTTGSTALEILNKEKFDLVLCDYRLDDTD
GKEILKYISESHPATGVIIITGYSDVKLAVELIKLGAYDYIVKPLYPDEILNTINKALEA
QQLLKKHKSTGNKIEATDFFNQPQYIEGKSKVSLNLLAQINVVAQTNYSIILTGKSGTGK
ECVAKAIHRNSLRSAGSFVAMDCGSLTKELAASEFFGHEKGSFTGALFTKIGHFEQANGG
TLFLDEVSNLSYEIQAILLRAVQERKIKRIGSTKEIDLDVRLIVATNENLEEGIQKGTFR
EDLYHRFNEFSIHVPSLKHRGNDILLFAERFLSIANQELNKKIKGFSDEVKKCLLANPWP
GNVRELKNVIRRVALLTDGDCIEPHVLPLEFGMIDHRSTQYEKKALLLPPKSHHEKSLHL
RNAAKEAEYNAILEVLKEVNFNKTKAAKILNIDRKTLYNKIKFRIDNGT