Protein Info for CA265_RS19680 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: DNA-binding transcriptional regulator OxyR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 310 PF00126: HTH_1" amino acids 4 to 61 (58 residues), 59.5 bits, see alignment E=2.5e-20 PF03466: LysR_substrate" amino acids 88 to 293 (206 residues), 122.2 bits, see alignment E=2e-39

Best Hits

KEGG orthology group: K04761, LysR family transcriptional regulator, hydrogen peroxide-inducible genes activator (inferred from 82% identity to phe:Phep_4220)

Predicted SEED Role

"Hydrogen peroxide-inducible genes activator" in subsystem DNA-binding regulatory proteins, strays or Oxidative stress or Thioredoxin-disulfide reductase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9Z9Q2 at UniProt or InterPro

Protein Sequence (310 amino acids)

>CA265_RS19680 DNA-binding transcriptional regulator OxyR (Pedobacter sp. GW460-11-11-14-LB5)
MTLVQLEYIVAVDTYRSFVTAADKCFVTQPTLSMQVQKLEELISVKIFDRSKQPVSPTEI
GAQIIAQARIILQESGKIKELISSQQQDVLGELRIGVIPTVAPYLLPEVISAMLDKYPEL
KLLIWEYTTEDIIHHLKTGVLDCGILATPLTDPNITETPLYYENFVSYISKNSKLYKKKA
VDAEDLNDENIWLLNEGHCMRNQVLNICRSTKNNRLQGLEYNTGSVETLVRMVDLNGGAT
LLPELAITELNAKQTNKIRHFKSPEPVREISLVTHKNFIKKRMLNALKDEILEIIPKTMK
QKKKKDIVGI