Protein Info for CA265_RS19540 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: tail-specific protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 729 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF17804: TSP_NTD" amino acids 54 to 237 (184 residues), 203 bits, see alignment E=1.1e-63 TIGR00225: C-terminal processing peptidase" amino acids 209 to 598 (390 residues), 285.9 bits, see alignment E=2e-89 PF00595: PDZ" amino acids 251 to 325 (75 residues), 38.1 bits, see alignment E=3.3e-13 PF03572: Peptidase_S41" amino acids 368 to 576 (209 residues), 141.8 bits, see alignment E=3.2e-45 PF11818: DUF3340" amino acids 582 to 712 (131 residues), 113.5 bits, see alignment E=2.1e-36

Best Hits

KEGG orthology group: K03797, carboxyl-terminal processing protease [EC: 3.4.21.102] (inferred from 74% identity to phe:Phep_0166)

Predicted SEED Role

"Tail-specific protease precursor (EC 3.4.21.102)" (EC 3.4.21.102)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.102

Use Curated BLAST to search for 3.4.21.102

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9ZCV9 at UniProt or InterPro

Protein Sequence (729 amino acids)

>CA265_RS19540 tail-specific protease (Pedobacter sp. GW460-11-11-14-LB5)
MDFKSFKEMLKRIFFVIFTAAVLACHAAPKTQPMVEGVTNVKPDEQQQLVIKEVVNLIES
YNYKKIQINDSISSIILDKYIKSLDQGKNYFLASDIKEFEKYRYTLDDDFKNGDLSGPFF
IYNVYAKRLNEYFTYSLAQIKTKYDFNQTDSYVYDREKQPWATSSAALNDTWKKRIKYEL
INLNLAGTAEAKNVETLTKRYQNLQSQTSKTNNQDVFQILMDAFTESIDPHTNYFNPTNA
AAFNEDMSRSFEGIGARLQLENEVVKISEIIAGGPAFKGKQLSAGDRIIAVAQGDGEFVD
VVGWRLDNTVSKIKGPKGTKVRLKVIPVGKEMSSKPVIIDLVRDKIVLEETSAKKKVKTI
NSNGKDYKIGIITLPAFYADFKAANAGDKNYKSTTRDVRKLIDSLKTYDKVNAIVMDLRG
NGGGSLVEAISLTGLFIDKGPVVQVKDLRGKIEVDEDENSGVAWDGPFGVMVDRLSASAS
EIFAGAIQDYGRGIIMGSQTYGKGTVQSSIDLNKLVNPSMLQRVAGLISKDKTVGTSPSG
ANPADINLGQINLTMAKFYRVAGSSTQHKGVTPDVVFPSVYPMDKIGEDTESSALPWDVI
PSSSFKPVANLTPVKAQLIKNSEQRIANSLDFKYLKQDIADLKKRDTEVSVTLNEAKLKA
ERDAQEAKTLARQNELRALRGLPAIKKGDKITKQDAFDFIEDESLKVMGDFMQQSGNYVM
NLGVMPKNN