Protein Info for CA265_RS19530 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: asparaginase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01112: Asparaginase_2
  • amino acids 2 to 271 (270 residues), 256.9 bits, E=1.3e-80

Best Hits

KEGG orthology group: K01424, L-asparaginase [EC: 3.5.1.1] (inferred from 67% identity to fps:FP1109)

Predicted SEED Role

"Isoaspartyl aminopeptidase (EC 3.4.19.5) @ Asp-X dipeptidase" (EC 3.4.19.5)

MetaCyc Pathways

• cyanophycin metabolism (6/6 steps found)
• L-asparagine degradation III (mammalian) (3/3 steps found)
• L-asparagine degradation I (1/1 steps found)
• superpathway of L-aspartate and L-asparagine biosynthesis (2/4 steps found)
• N-(1-deoxy-D-fructos-1-yl)-L-asparagine degradation (2/5 steps found)

KEGG Metabolic Maps

• Alanine and aspartate metabolism
• Cyanoamino acid metabolism
• Nitrogen metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.4.19.5, 3.5.1.1

Use Curated BLAST to search for 3.4.19.5 or 3.5.1.1

Sequence Analysis Tools

See A0A1X9Z9R5 at UniProt or InterPro

Protein Sequence (280 amino acids)

>CA265_RS19530 asparaginase (Pedobacter sp. GW460-11-11-14-LB5)
MKLIIHGGFFSESSTNQETKKAKQDALASIVTLGHEYLKTHTALETVVYTVALLEDNELF
NAGIGSQIQSDGKVRLSAALMDGKTEKFSGVINVEEVKNPIQIAQHLLPYDDRVLSGDGA
QQFARANGFEYFNPITAQRQSEYEAKLNQKNNKGTVGCVALDADGNLAAATSTGGKGFEI
PCRVSDSATVAGNYANQYAGISCTGVGEDIVSGALAAKIVTRVTDGFSLKDASDKSFAEL
KAFDGFAGIVGISAAGEVYHCDSHPYMVWASFDVNLQVFS