Protein Info for CA265_RS17645 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: efflux transporter periplasmic adaptor subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 365 transmembrane" amino acids 6 to 23 (18 residues), see Phobius details TIGR01730: efflux transporter, RND family, MFP subunit" amino acids 60 to 360 (301 residues), 262.9 bits, see alignment E=1.7e-82 PF16576: HlyD_D23" amino acids 66 to 280 (215 residues), 94 bits, see alignment E=1.3e-30 PF13533: Biotin_lipoyl_2" amino acids 80 to 123 (44 residues), 24.4 bits, see alignment 2.9e-09 PF13437: HlyD_3" amino acids 177 to 277 (101 residues), 56.3 bits, see alignment E=7.3e-19

Best Hits

KEGG orthology group: None (inferred from 69% identity to phe:Phep_3735)

Predicted SEED Role

"Probable Co/Zn/Cd efflux system membrane fusion protein" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9Z7Y6 at UniProt or InterPro

Protein Sequence (365 amino acids)

>CA265_RS17645 efflux transporter periplasmic adaptor subunit (Pedobacter sp. GW460-11-11-14-LB5)
MKKRYIIYAVLAIGLAYLVYYRINANKKLEGKGGASAGAGKGKEGGKGGSSAPLVVDGIV
VKPVSFDNDLEVTGAIDANESVVLKSEVSGLVTGIYFQEGTTVSKGSVLVKVNDRDIQAQ
LQDALTKQKLSGTNENRAKQLLAKGAISQEEYDTALADLKSLQAQAQLIRAQLAKTTIRA
PFTGRVGLRSISAGTYLTPATVIANLVSTNPVKVTFSVPEKYAGQIKMNSEIIFTTDGSS
KENKGKVYAIEPGINAATRTLQIRALAPNADNALLPGSFAKIKLALNTVQNAILIPNEAV
IPVLKGKIVYIQKDGKAQEVKVEAGTRTDENIVITSGLKAGDTVLTTGSMALKKDAPVKV
HLVKQ