Protein Info for CA265_RS16470 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 157 PF02590: SPOUT_MTase" amino acids 1 to 155 (155 residues), 185.3 bits, see alignment E=3.7e-59

Best Hits

Swiss-Prot: 60% identical to RLMH_PARD8: Ribosomal RNA large subunit methyltransferase H (rlmH) from Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152)

KEGG orthology group: K00783, hypothetical protein (inferred from 80% identity to phe:Phep_0655)

Predicted SEED Role

"LSU m3Psi1915 methyltransferase RlmH" in subsystem Ribosome biogenesis bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9Z801 at UniProt or InterPro

Protein Sequence (157 amino acids)

>CA265_RS16470 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH (Pedobacter sp. GW460-11-11-14-LB5)
MKITLIAIGKTEDKYLIEGIDKYINRLKHYINFSFVALPDVKNVKNLSEAQQKAKEAELL
HKQINNGDVVILLDEKGKKYSSVEFSNYLNKQMIGSVQHLIFIIGGPYGFDESIYKRANG
LISLSDMTFSHQMIRLFFVEQLYRGFSILKGEPYHHA