Protein Info for CA265_RS12060 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: beta-galactosidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 954 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF02837: Glyco_hydro_2_N" amino acids 34 to 206 (173 residues), 57.6 bits, see alignment E=2.4e-19 PF00703: Glyco_hydro_2" amino acids 228 to 337 (110 residues), 38 bits, see alignment E=3.9e-13 PF02836: Glyco_hydro_2_C" amino acids 342 to 492 (151 residues), 31.6 bits, see alignment E=1.4e-11

Best Hits

KEGG orthology group: None (inferred from 54% identity to shg:Sph21_5085)

Predicted SEED Role

"Beta-galactosidase (EC 3.2.1.23)" in subsystem Galactosylceramide and Sulfatide metabolism or Lactose and Galactose Uptake and Utilization or Lactose utilization (EC 3.2.1.23)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.23

Use Curated BLAST to search for 3.2.1.23

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9Z533 at UniProt or InterPro

Protein Sequence (954 amino acids)

>CA265_RS12060 beta-galactosidase (Pedobacter sp. GW460-11-11-14-LB5)
MKNNILRLGMLSLALLSLIHTAAAQSKNNAHIELSGIWNFQVDSLDKGVDEKWFNKELND
KIKLPGSMTTNGKGNDITVNTKWTGQIVDKSWFTSDEYAKYRQPDNIKIPFWLQPTKSYV
GAAWYQKTVNIPAAWKNKRIQLLIERSHWETTVWVDGVEVGTNNSLATAQLFDLGNKLTP
GSHRVTVKIDNSSKSFKVGENAHSISDHTQTNWNGMVGELSLIARANVFIDDVQLYPDVK
NKQVLAKIQVKNTTGAPVSIGLNLLATANRSTGAKLKPLSKNVIVAEKERTIEMVYPMGA
TPQLWNEFHPDLYEMRVNLNMGKQGEIDARKITFGMREFKAKGTQFAINDELTFLRGALD
CAAFPKTGFPPTDVDSWMKNFKTIKAYGLNHVRFHSWCPPEAAFIAADRLGLFLQVECDA
WANSYKGSYIGDGLPLDKYVYQESERMVKAYGNHPSFVMMTYGNEPSGKGQVKYLVDFVN
YWKAKDPRRMYTTAAGWPQNDASDYNNMPEPRIQGWGQGLKSIINSEAPKSDYDWTKTIA
KWKQPTVSHEIGQWCVYPNFNEIKKYDGVLKAKNFEIFKDRLQENGLSMLADSFFMASGK
LQSLCYKADIEAALRTPGFAGFQLLGLNDFPGQGTALVGVLDAFWESKPYISASEYSRFC
APIVLLARLPKMVYNNDEDLAVPIEIANFSDNVLKNAATNWVIENEKGEKLFNGSFKNET
VGIGNGIKIGTIKQSLTSIKTPQRLILKTTIGNHSNEWEIFVYPKTLPEAPKEILLTQTL
DDNAVATLNSGGKVLLTLKKGSVKAEMGGDIKIGFSTIFWNTAWTHSQPPTTMGILCNPT
HPALAEFPTQYHSNWQWWDAMTHSSAIKLNSVSKDLKPIVRVVDDWFTARPLGLVFECNV
EKGKLLVSSIDLLSDQDKRPEARQLLYSLEKYMTGSQFKPKDHINLDKIQELVN