Protein Info for CA265_RS11115 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: polyphosphate kinase 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 679 PF13089: PP_kinase_N" amino acids 6 to 110 (105 residues), 104.2 bits, see alignment E=1.1e-33 TIGR03705: polyphosphate kinase 1" amino acids 6 to 670 (665 residues), 681 bits, see alignment E=9.5e-209 PF02503: PP_kinase" amino acids 121 to 295 (175 residues), 143.1 bits, see alignment E=2e-45 PF17941: PP_kinase_C_1" amino acids 320 to 483 (164 residues), 221.1 bits, see alignment E=1.7e-69 PF13091: PLDc_2" amino acids 351 to 473 (123 residues), 36.1 bits, see alignment E=1.4e-12 PF13090: PP_kinase_C" amino acids 496 to 658 (163 residues), 229.1 bits, see alignment E=6e-72

Best Hits

KEGG orthology group: K00937, polyphosphate kinase [EC: 2.7.4.1] (inferred from 55% identity to phe:Phep_2480)

Predicted SEED Role

"Polyphosphate kinase (EC 2.7.4.1)" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism or Purine conversions (EC 2.7.4.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.4.1

Use Curated BLAST to search for 2.7.4.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9ZDB8 at UniProt or InterPro

Protein Sequence (679 amino acids)

>CA265_RS11115 polyphosphate kinase 1 (Pedobacter sp. GW460-11-11-14-LB5)
MVETSFFNRDLSWLKFNERILMEAERNTVPLLERIKFLSIFSSNLDEFYRVRMPVLLALE
KLSNKEDNDIQIDDNLLSTANQLISEQQQRYGKVLKSDLIPLLKENKINLIYGQAFPAEI
QKSITRYFLSQVMAFLQPVYINANTNFFPSNNELYFLITLKKKEDAEVVILNIPSNQLPR
FYKVETGDETFIVFLDDIVRFHLDRIFPEGEVTGCYSFKITRDAEIDLKDEYSGSLSEQL
EKQLLKRDSGLATRFLHQPGIPANVFELLKKLFNLKKANRMEGGQYHNLKDFMGFPVNSP
KLSNQNWPKLCNTDLIDGSLTEAIYKNDIMVHTPYQSYDSVLRFFNEAAIDAEVREIYVT
LYRVASDSKIVNALISAAKNGKKVTVLVELKARFDEANNIKWAKKMKEVGVDIIYSVTAL
KVHAKVALVKRQVGNRMRYSGLFSTGNFNESTAAFYTDHILMTANKEMLREVELLFIFLA
KRVKPTSADLIKFNHLLVAQFNLQQVFLNLIDREIEHAKQGKPSGITIKMNNLEEKVLID
KLYEASSAGVKIDMIVRSICRLIPGVPGMSENIKITRIVDRYLEHGRIFIFNNLGKNDVY
LGSADWMNRNIYRRIEVCFPIYNEQIKQEMIDIIEIQKQDNVQAVCIDENMNNIPVKRSG
TLVESQHDIYQLLKKNNAV