Protein Info for CA265_RS07845 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: signal transduction protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 483 PF00571: CBS" amino acids 14 to 65 (52 residues), 26.4 bits, see alignment 1e-09 amino acids 80 to 132 (53 residues), 35.1 bits, see alignment 2.1e-12 PF03445: DUF294" amino acids 158 to 295 (138 residues), 141.2 bits, see alignment E=3e-45 PF10335: DUF294_C" amino acids 335 to 478 (144 residues), 120.9 bits, see alignment E=5.9e-39

Best Hits

KEGG orthology group: K07182, CBS domain-containing protein (inferred from 61% identity to shg:Sph21_5126)

Predicted SEED Role

"Predicted signal-transduction protein containing cAMP-binding and CBS domains" in subsystem cAMP signaling in bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9Z2Y2 at UniProt or InterPro

Protein Sequence (483 amino acids)

>CA265_RS07845 signal transduction protein (Pedobacter sp. GW460-11-11-14-LB5)
MEDKLADQIYTARIGDITFKKIVSCSPGTPIFEAAIKMSEQKTSCLFIKNDQDVYLGFVT
DITLRDNVIAKQLNPNLPIDEVMDTHIVTISPDAYVYEAILMMFSKKSRYLLVNDNGNYV
GFLSRNRLLSEQAESPLVFIQSVKSAVNTSDLKLKWQKVPNIVAQLLARGVHSKIVNEVV
TTIADTISFKIIEEVIAKLGPPPAKFVFMVLGSEGRKELSLKTDQDNAIIYEDTGEDKRA
AVRSYFLDLATQVSDKLNFVGFVYCDGDYMATNPNWTHSLSHWKYNYKNWIEEALPEAAV
KFAAFFDCRAIYGDLTIMESLRSFVDEELQKPIEKFYVYLAKNALLYEPPLTYFRNIRTQ
KIHKKEVFDIKTAMTPIVDLARVYALQNRIFQKENTGERLKALRELGVFSEEQFNELSQS
YYYLMGLRLKHQANLIINDQAAPNNFIEIDSLTKIEKVTLIEIFKIIQNFQSGIRMKFTN
SLG