Protein Info for CA265_RS07790 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: recombinase RecQ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 630 TIGR00614: ATP-dependent DNA helicase, RecQ family" amino acids 5 to 336 (332 residues), 387 bits, see alignment E=6.4e-120 PF00270: DEAD" amino acids 17 to 176 (160 residues), 91.5 bits, see alignment E=8e-30 PF00271: Helicase_C" amino acids 213 to 318 (106 residues), 69.5 bits, see alignment E=4.3e-23 PF16124: RecQ_Zn_bind" amino acids 518 to 563 (46 residues), 41.8 bits, see alignment 2.2e-14

Best Hits

KEGG orthology group: K03654, ATP-dependent DNA helicase RecQ [EC: 3.6.4.12] (inferred from 70% identity to phe:Phep_1902)

Predicted SEED Role

"ATP-dependent DNA helicase, RecQ family" in subsystem DNA repair, bacterial RecFOR pathway

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.12

Use Curated BLAST to search for 3.6.4.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9Z2T6 at UniProt or InterPro

Protein Sequence (630 amino acids)

>CA265_RS07790 recombinase RecQ (Pedobacter sp. GW460-11-11-14-LB5)
MTAIEILQKYWGHQAFRPLQEDIISSVLEGNDSLALLPTGGGKSICFQVPALVKEGICIV
VSPLIALMKDQVEHLKSKGIEAIAIYAGMGKREIDILLDNCIYGKIKFLYLSPERLLSDL
VRVRISYMNVNLIAVDEAHCISQWGYDFRPPYQQLSKLREILPNVPVLALTATATAFVRK
DIVEKLEMKDPKVFVKSFARDNLSYVVFGNEDKYKKLIDICKNVKGTGLVYVRNRRETAE
VSNFINRNQIKADFYHAGLERDTRFLKQEEWKNNKTRIMVATNAFGMGIDKADVRFVVHL
DLPESLEAYYQEAGRAGRDEKRSYAVLLANQSDVLGLESRYLDSFPSPDEIRKTYHYLGN
YFQLAFGAGEGLTFTFDIADFCKRFNISVLKTISALKFLEHDGYLTLSESVFLPSRMMFI
ASHEDIYRFQIENKAYDGIIKTILRSHGGAFDGFVKINEADLAKKTGLSYKEIIALLNKL
QAIELLTYIQQTDQPQLQYIRPRVDMDHFDLDVKYLELRKEILHKQINAVVGYASSNLCR
SVQLLNYFDEHHATKCGVCDVCLAEKRTENQSQIGEALEFEIVSLLQQQALSLDDLVTNI
KNGAEAERIDAIRELLDAGKIKSDGKKYYL