Protein Info for CA265_RS07460 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: deoxynucleoside kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01712: dNK
  • amino acids 3 to 199 (197 residues), 212 bits, E=4.3e-67

Best Hits

Swiss-Prot: 38% identical to DGK2_LACAC: Deoxyguanosine kinase (LBA1950) from Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM)

KEGG orthology group: None (inferred from 91% identity to phe:Phep_2581)

Predicted SEED Role

"Deoxyadenosine kinase (EC 2.7.1.76) / Deoxyguanosine kinase (EC 2.7.1.113)" in subsystem Purine conversions or PnuC-like transporters (EC 2.7.1.113, EC 2.7.1.76)

MetaCyc Pathways

• purine deoxyribonucleosides salvage (6/6 steps found)

KEGG Metabolic Maps

• Purine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.113 or 2.7.1.76

Sequence Analysis Tools

See A0A1X9Z2M8 at UniProt or InterPro

Protein Sequence (204 amino acids)

>CA265_RS07460 deoxynucleoside kinase (Pedobacter sp. GW460-11-11-14-LB5)
MHIAIVGNIGAGKTTLTGLLAKNYGWEALYEAVDNNPYLEDFYSDMKRWSFNLQIYFLNS
RFQQITDIEVNKRNVIQDRTIYEDAHIFAENLHDMALMTTRDHDNYRAIFDNITSFIKPP
DLLVYLRASVPTLVNNIQRRGREYEAGIRIDYLSKLNEKYEAWIKGYNLGKLLILDKDKL
DFTNNPEDLGTVIQSIEAEINGLF