Protein Info for CA265_RS07185 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: glycoside hydrolase family 2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 884 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF02837: Glyco_hydro_2_N" amino acids 33 to 173 (141 residues), 47.8 bits, see alignment E=4.1e-16 PF00703: Glyco_hydro_2" amino acids 188 to 293 (106 residues), 69.8 bits, see alignment E=8.1e-23 PF02836: Glyco_hydro_2_C" amino acids 300 to 601 (302 residues), 105.9 bits, see alignment E=5.8e-34 PF16355: DUF4982" amino acids 631 to 684 (54 residues), 40 bits, see alignment 7.7e-14 PF11721: Malectin" amino acids 718 to 872 (155 residues), 59.3 bits, see alignment E=1.2e-19

Best Hits

KEGG orthology group: K01190, beta-galactosidase [EC: 3.2.1.23] (inferred from 52% identity to sli:Slin_0624)

Predicted SEED Role

"Beta-galactosidase (EC 3.2.1.23)" in subsystem Galactosylceramide and Sulfatide metabolism or Lactose and Galactose Uptake and Utilization or Lactose utilization (EC 3.2.1.23)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.23

Use Curated BLAST to search for 3.2.1.23

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9Z2H8 at UniProt or InterPro

Protein Sequence (884 amino acids)

>CA265_RS07185 glycoside hydrolase family 2 (Pedobacter sp. GW460-11-11-14-LB5)
MKKSSLRSKSLLLLLIAAITGLSTYAQDAGRKTISLNDQWEFNKENGPVEKVNIPHTWND
KDVLDDVPGYYRGLGIYKRKLKLDESAKGKAIFLVFNSVAQEAEVLVNGKSAGKHIGSYT
RFIVPISSFLNFKDDVIEVRANNRFNEDIPPLTADFTFFGGLYRNVTLLMTNPLHFSQKE
NGSSGVFITTPQVSASTASVQVKSSVDNTATTSQKVQVMTTIFDANGKMVTSQNTTANVN
KGGNTVVIQDIKAIQKPQLWSPENPYLYRLVTKIIDPKTKSVIDQVSNPLGFRWFKFDAD
KGFFLNDQPVKIIGASRHQDYENRGNATPDALQIKDIELLKAMGGNFLRVAHYPQDPQIL
EACDRLGILASVEIPVVNTITESEAFTTNCLNMQTEMIKQNFNHPSIIIWAYMNEILLRL
KFSNDKPRQQIYFDHVRELAQKLDSLTRKLDPSRYTLLVNHGAWDIYNKVGLTKIPMIVG
WNLYSGWYSGVPEDFAKFLDRHHKELPHTPFMVTEFGADADPRIRSFSPIRFDKSVEYGI
KFNQVYLSAMRSRPFVAGGQAWNLADFNSETREETMPHINNKGLLTIGREPKDTYFLYQA
YLLGKPFIKITSAQWKDRTGIADSATLTSTQPIQVATNLKSAELFLNGKSLGLKEAVDHI
IDWQVPFVNGKNQLRVVAGDQNDQADIHFQLQPFKFNDADIPFKNINILLGSKRFYIDEK
EQQLWMPDQPYKTGAWGWIGGEPYKGTNNRITYGSDKNILGTDNDPVYQTQQVGIKQFKF
DVPDGEYELALHFAELVGGETKEALAYNLDNNHKKEIEEQRIFDVSVNGILLMSKVNLAS
NFGYTTAVKKTTRITVQNGKGILIEFKAIEGKAVLNAVQLRKIY