Protein Info for CA265_RS06870 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: efflux transporter periplasmic adaptor subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 360 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details TIGR01730: efflux transporter, RND family, MFP subunit" amino acids 40 to 342 (303 residues), 224.8 bits, see alignment E=6.7e-71 PF16576: HlyD_D23" amino acids 57 to 260 (204 residues), 64.5 bits, see alignment E=1.7e-21 PF13533: Biotin_lipoyl_2" amino acids 57 to 102 (46 residues), 28 bits, see alignment 2.9e-10 PF00364: Biotin_lipoyl" amino acids 58 to 88 (31 residues), 22.4 bits, see alignment (E = 1.8e-08) PF13437: HlyD_3" amino acids 154 to 260 (107 residues), 32.6 bits, see alignment E=2.2e-11

Best Hits

KEGG orthology group: K03585, membrane fusion protein (inferred from 74% identity to phe:Phep_2953)

Predicted SEED Role

"Probable Co/Zn/Cd efflux system membrane fusion protein" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9Z2Q6 at UniProt or InterPro

Protein Sequence (360 amino acids)

>CA265_RS06870 efflux transporter periplasmic adaptor subunit (Pedobacter sp. GW460-11-11-14-LB5)
MKRVVMCLGLCTLLYVTGCTSKKEEKEEVATYAVTTPLKMDTSFTKEYVSQIKSVRNIEV
RAQEKGYLQNIYVDEGQHVKAGQLLFKIMPKAAQSELLKAQAETKSAEIELENTKLLSDK
NIVSKNELAMAKAKLQSANAETSLAKFHLSNTEIRAPFEGTIDRIPLKLGSLVDEGALLT
SLSDNSQVFAYFNVSEPEYLNYQSTAKAKGQQEVSLLLANNELLKSKGKVEVIESEFDNE
TGNIAFRARFNNSDNLLRNGETGKIQMVVPLKNALVIPQKATYDIQDKTYVFVIDKNNKV
HSRAITIAGDLPDLYIVGDGITTGDKILLEGVQKVKDDDKIAFKFQQPQEVMKQLRLKTE