Protein Info for CA265_RS04500 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: short-chain dehydrogenase/reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 268 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF00106: adh_short" amino acids 3 to 184 (182 residues), 165 bits, see alignment E=4.5e-52 PF08659: KR" amino acids 4 to 157 (154 residues), 43.7 bits, see alignment E=8.7e-15 PF05368: NmrA" amino acids 5 to 67 (63 residues), 23 bits, see alignment E=1.4e-08 PF01370: Epimerase" amino acids 5 to 160 (156 residues), 33.1 bits, see alignment E=1.2e-11 PF13460: NAD_binding_10" amino acids 9 to 78 (70 residues), 32.9 bits, see alignment E=1.8e-11 PF13561: adh_short_C2" amino acids 9 to 188 (180 residues), 122.3 bits, see alignment E=7.8e-39

Best Hits

KEGG orthology group: None (inferred from 81% identity to shg:Sph21_4374)

Predicted SEED Role

"Short-chain dehydrogenase/reductase SDR"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9Z1C0 at UniProt or InterPro

Protein Sequence (268 amino acids)

>CA265_RS04500 short-chain dehydrogenase/reductase (Pedobacter sp. GW460-11-11-14-LB5)
MQKTIFITGASSGLGKATAELFHAKGWSVIATMRNPEKESKLKELPNVTLVKLDVTDAAA
IQKTVSTILQSYAVDVVLNNAGYGLIGPLEALKDEQILSQVQTNLFGVINVTRAFLPYFR
ESRSGSFINVTSTFGLLGYPTCSIYNATKFAVDGFSEGLAYELAQFGIKVKVVAPGGMQT
DFAGRSLQGGMHEAYTQLVAKVSEGYSEEQIANYSKADDVAQIIYEAATDDKKQLRYIAG
NDAIGLYKERLELTPEGQFEKIRSQFIF