Protein Info for CA265_RS04435 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: transcription termination factor Rho

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 580 TIGR00767: transcription termination factor Rho" amino acids 4 to 579 (576 residues), 645.1 bits, see alignment E=2.3e-198 PF07498: Rho_N" amino acids 6 to 43 (38 residues), 32.1 bits, see alignment 1.4e-11 PF07497: Rho_RNA_bind" amino acids 217 to 289 (73 residues), 114.5 bits, see alignment E=2.3e-37 PF00006: ATP-synt_ab" amino acids 322 to 526 (205 residues), 95.4 bits, see alignment E=6.2e-31

Best Hits

Predicted SEED Role

"Transcription termination factor Rho" in subsystem Transcription factors bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9Z166 at UniProt or InterPro

Protein Sequence (580 amino acids)

>CA265_RS04435 transcription termination factor Rho (Pedobacter sp. GW460-11-11-14-LB5)
MFSKTELNDKLTTELRELAKSYGIEGADSLRKIDLVEVLLHQQEIINAAKAGADPYSDIE
PIAATPAPKTKATKTPKVAAAAAAAASTVVADKPAATTTDKPVKKRARLTKDEPAAPIER
RRDAVTLFDEPQHQQQPERQPDRIIEAEESVKPISALIEESAEVLPVAPKQKQEPKEKQE
KPQRDENRQQKQPGGGNHHKNENSYSNLDFDNVITNEGVLEIMPDGYGFLRSADYNYLTS
PDDIYVSQSQIKLFGLKTGDTVKGSIRPPKEGEKYFPLVRVETINGRIPAEVRDRVPFDY
LTPLFPTERLNLFTDTNNYSTRIMDLFTPIGKGQRGLIVAQPKTGKTNLLKEVANAIAKN
HPEVYLIILLIDERPEEVTDMARSVRAEVIASTFDEPAERHVKIANIVLEKSKRLVESGH
DVVILLDSITRLARAYNTTAPASGKILSGGVDANALHKPKRFFGAARNIENGGSLTILAT
ALTDTGSKMDEVIFEEFKGTGNMELQLDRKLSNKRIFPAIDITASSTRRDDLLHDRDTLQ
RVWILRNHLADMNSQEAMEFVQSQIKGTKSNEEFLISMNS