Protein Info for CA265_RS03260 in Pedobacter sp. GW460-11-11-14-LB5
Annotation: multidrug ABC transporter ATP-binding protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 37% identical to NATA_BACSU: ABC transporter ATP-binding protein NatA (natA) from Bacillus subtilis (strain 168)
KEGG orthology group: K09687, antibiotic transport system ATP-binding protein (inferred from 69% identity to phe:Phep_3248)MetaCyc: 37% identical to Na+ ABC efflux transporter ATP-binding protein (Bacillus subtilis subtilis 168)
RXN-17739 [EC: 7.2.2.3, 7.2.2.4]
Predicted SEED Role
"ABC-type multidrug transport system, ATPase component"
Isozymes
No predicted isozymesUse Curated BLAST to search for 7.2.2.3 or 7.2.2.4
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A1X9Z0S3 at UniProt or InterPro
Protein Sequence (235 amino acids)
>CA265_RS03260 multidrug ABC transporter ATP-binding protein (Pedobacter sp. GW460-11-11-14-LB5) MSISVKNLSKHYDKQKAVDSISFEAKPGRILGFLGPNGAGKSTTMRMLTGYLEPTSGEAE ISGKSILSEAIEAKKHIGYLPENTPLYADMYVKEFLNFVGQTYKLSHLPTRIDEVIKMVG LTAEQHKKIGMLSKGYRQRVGLAQAIIHNPEVLILDEPTSGLDPNQLVDIRQLIKTLGAA KTVIISTHIMQEVEAICDDIIIISKGKIVAKDSLEGLKKNHQQQSLEDIFRKLTA