Protein Info for CA265_RS02925 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: sulfatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 533 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF00884: Sulfatase" amino acids 23 to 417 (395 residues), 188.1 bits, see alignment E=3.6e-59 PF16347: SGSH_C" amino acids 364 to 516 (153 residues), 199.3 bits, see alignment E=6.5e-63

Best Hits

Predicted SEED Role

"Choline-sulfatase (EC 3.1.6.6)" in subsystem Choline Transport or Choline and Betaine Uptake and Betaine Biosynthesis (EC 3.1.6.6)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 3.1.6.6

Use Curated BLAST to search for 3.1.6.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9Z0J4 at UniProt or InterPro

Protein Sequence (533 amino acids)

>CA265_RS02925 sulfatase (Pedobacter sp. GW460-11-11-14-LB5)
MKNFFLFLFLCFQATVFAQNKRPNIIFILSDDHAYQAISAYGNKLIHTPNIDKLAKSGTL
FNNAIVSNAICGPSRAAFITGQYSHKNGYKVNDGVLDTNQRFLPQILNENGYQTAWIGKW
HLGSLPQGFDYWNVMPVQGHYFNPDFINQKNDTLLYHGYVTEVITELTKNYLNKRNPDKP
FFLVVGEKATHREWLPDLQDLGAYDSIKFPLPATFYDDYKGRTAASKQLMSIGEAMTIKT
DLKINQPFGEKVNVGKATKPAVKGKEIEESMMRYYQQGEYSRMDSLQSKAYRAYYGQLSK
AFQQLYLTGNALKEWKFQRYMKDYYATAKSLDRNIGEILDYLDRNGLSENTIVIYASDQG
FYLGEHGWFDKRFIYEESLRTPFIIRVPGLSAMKDKKLDQIISNVDWAPTILDFAGISKP
GFMQGRSFLPVLENPKIKNWKKEGAYYHYYEYPGPHYVSPHFGIRTDGYVLARFYKGTEA
WEMYDLKKDPKELKNIIEDKNYFVIKNELKKKLKALIIAYDDKEALKVFNQNL