Protein Info for CA265_RS01375 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: cytochrome C oxidase Cbb3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 713 transmembrane" amino acids 12 to 38 (27 residues), see Phobius details amino acids 59 to 78 (20 residues), see Phobius details amino acids 98 to 116 (19 residues), see Phobius details amino acids 129 to 149 (21 residues), see Phobius details amino acids 156 to 176 (21 residues), see Phobius details amino acids 203 to 225 (23 residues), see Phobius details amino acids 234 to 253 (20 residues), see Phobius details amino acids 267 to 292 (26 residues), see Phobius details amino acids 304 to 321 (18 residues), see Phobius details amino acids 341 to 365 (25 residues), see Phobius details amino acids 378 to 400 (23 residues), see Phobius details amino acids 433 to 454 (22 residues), see Phobius details amino acids 499 to 519 (21 residues), see Phobius details TIGR00780: cytochrome c oxidase, cbb3-type, subunit I" amino acids 7 to 471 (465 residues), 649.1 bits, see alignment E=4.4e-199 PF00115: COX1" amino acids 11 to 441 (431 residues), 383.9 bits, see alignment E=1e-118 PF02433: FixO" amino acids 489 to 702 (214 residues), 332.8 bits, see alignment E=9.1e-104 TIGR00781: cytochrome c oxidase, cbb3-type, subunit II" amino acids 489 to 706 (218 residues), 252.4 bits, see alignment E=4.4e-79

Best Hits

KEGG orthology group: K00404, cb-type cytochrome c oxidase subunit I [EC: 1.9.3.1] K00405, cb-type cytochrome c oxidase subunit II [EC: 1.9.3.1] (inferred from 80% identity to psn:Pedsa_0368)

Predicted SEED Role

"Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) / Cytochrome c oxidase subunit CcoO (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YZW8 at UniProt or InterPro

Protein Sequence (713 amino acids)

>CA265_RS01375 cytochrome C oxidase Cbb3 (Pedobacter sp. GW460-11-11-14-LB5)
MQLEKFTYDNKIVRNFGIATLVWGIIGMTVGLLVAMQLFKPAMNMGSQYTTFGRIRPLHT
NAVIFAFVGNAIFMGVYYSLQRLLKARMFSDALSKIHFWGWQLIILSAVITLPLGFTTSH
EYAELEWPIDIAITIIWVVFGVNMFGTIFKRRERHLYVAIWFYIATFVTIAVLHIVNSFE
LPISFMKSYYVYAGVQDALVQWWYGHNAVAFFLTTPYLGMMYYFLPKMAGRPVYSYKLSI
LHFWSLIFIYIWAGPHHLLYTSLPGWAQSLGVAFSIMLIAPSWGGMINGLLTLRGAWDKV
REDVTLKFMVVALTAYGMATFEGPLLSLKQINGVAHFTDWIVAHVHVGALGWNGFLTFGV
LYWLIPRIYKTELYSKKLAGFHFWIGTLGILFYAVPMYWAGFTQGLMWKEFTPEGLLKYP
NFLATTLQIIPMHVLRSIGGALYLIGVIAMTYNLAKTMLRAKLLANEPAEAMPLTKIIVE
TSPADKAWHRVLERKPMKFMVLSLIIILIGGMVEMMPTFTIQSNVPTIASVKSYSALELQ
GRDLYIREGCVNCHSQTVRPFRSETERYGEYSKAGEFVYDHPFLWGSKRTGPDLHRIGGK
YSDAWHYNHLVDPASMSPGSIMPPYPWLIEQKLDITTTASKIRAMQTLGVPYPEGYDKRA
NDDLKVQAEKIALELKQNNIKVKSDREIVAIIAYLQRLGTDIKANKENIPSNQ