Protein Info for BWI76_RS27680 in Klebsiella michiganensis M5al

Annotation: TetR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 215 transmembrane" amino acids 166 to 184 (19 residues), see Phobius details PF00440: TetR_N" amino acids 30 to 74 (45 residues), 49.9 bits, see alignment 1.1e-17

Best Hits

KEGG orthology group: None (inferred from 78% identity to eae:EAE_06735)

Predicted SEED Role

"Transcriptional regulator RutR of pyrimidine catabolism (TetR family)" in subsystem Pyrimidine utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285BBR4 at UniProt or InterPro

Protein Sequence (215 amino acids)

>BWI76_RS27680 TetR family transcriptional regulator (Klebsiella michiganensis M5al)
MSAQKDNEAPRRPGRPRGQKSGPANREQLMDIALALFARHGIARISLNAIAKEAGVTPAM
LHYYFSSREALVEKLIEERFMPLRSEIGQIFVAHGDDPVTAFTLLIETLAAMAEKNAWFA
PLWMQEIIGEMPVLRQQMHARFGDEKYHKMLETVRRWQQQGKLNPALSPELLFTTLISLV
LVPFSRTHTDPRLQSVDKQMIVSHALALIGSGIGG