Protein Info for BWI76_RS27425 in Klebsiella michiganensis M5al
Annotation: DNA-directed RNA polymerase subunit omega
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 99% identical to RPOZ_KLEP7: DNA-directed RNA polymerase subunit omega (rpoZ) from Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
KEGG orthology group: K03060, DNA-directed RNA polymerase subunit omega [EC: 2.7.7.6] (inferred from 99% identity to eco:b3649)Predicted SEED Role
"DNA-directed RNA polymerase omega subunit (EC 2.7.7.6)" in subsystem RNA polymerase bacterial (EC 2.7.7.6)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.7.7.6
Use Curated BLAST to search for 2.7.7.6
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A285BBL5 at UniProt or InterPro
Protein Sequence (91 amino acids)
>BWI76_RS27425 DNA-directed RNA polymerase subunit omega (Klebsiella michiganensis M5al) MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKTTVIALREIEEGLIN NKILDVRERQEQQEQEAAELQAVTAIAEGRR