Protein Info for BWI76_RS27235 in Klebsiella michiganensis M5al
Annotation: murein hydrolase activator EnvC
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 86% identical to ENVC_ECOLI: Murein hydrolase activator EnvC (envC) from Escherichia coli (strain K12)
KEGG orthology group: None (inferred from 94% identity to kpu:KP1_5307)MetaCyc: 86% identical to murein hydrolase activator EnvC (Escherichia coli K-12 substr. MG1655)
Predicted SEED Role
"Periplasmic septal ring factor with murein hydrolase activity EnvC/YibP"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A285BBK1 at UniProt or InterPro
Protein Sequence (423 amino acids)
>BWI76_RS27235 murein hydrolase activator EnvC (Klebsiella michiganensis M5al) MRGKATYSTTWIATAVRSVLYASALSAGVLLCAASAHADDRDQLKSIQADIAAKQRAIKQ QQQQRASLVAQLKAQEEAISAAARKLRETQETLNQLNKQIDEMNAALAKLERQRASQERN LSAQLDAAFRQGPHTGIQMILSGEEGQRNQRMQAYFGYLNQARQETIAELKKTREDVAVQ KSMLEEKQSQQQTLVYEQRAQQSKLEQARNERKKTLASLESSIQQGQQQLSEMRANESRL RGRIAQAAAAAKARADREAREAQDVRDRQQEASRKGTTYKPTESERSLMSRTGGLGSPRG QAFWPVRGSILHRYGEQLQGELRWKGMVIAASEGTEVKAVADGRVILADWLQGYGLVVVV EHGKGDMSLYGYNQSALVSVGTQVRAGQPIALVGSSGGQGRPSLYFEIRRQGQAVNPQPW LGR