Protein Info for BWI76_RS26770 in Klebsiella michiganensis M5al

Annotation: cellulose biosynthesis protein BcsC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1161 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF13432: TPR_16" amino acids 275 to 338 (64 residues), 31.5 bits, see alignment 1.3e-10 amino acids 357 to 419 (63 residues), 30 bits, see alignment 3.8e-10 amino acids 609 to 668 (60 residues), 30.8 bits, see alignment 2e-10 PF14559: TPR_19" amino acids 281 to 338 (58 residues), 26.8 bits, see alignment 3.2e-09 amino acids 616 to 668 (53 residues), 38.1 bits, see alignment 9.4e-13 PF13181: TPR_8" amino acids 308 to 336 (29 residues), 17.7 bits, see alignment (E = 1.9e-06) PF05420: BCSC_C" amino acids 803 to 1140 (338 residues), 406.1 bits, see alignment E=7.4e-125

Best Hits

Swiss-Prot: 69% identical to BCSC_SALTY: Cellulose synthase operon protein C (bcsC) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: None (inferred from 84% identity to eae:EAE_05910)

Predicted SEED Role

"Cellulose synthase operon protein C"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285BB30 at UniProt or InterPro

Protein Sequence (1161 amino acids)

>BWI76_RS26770 cellulose biosynthesis protein BcsC (Klebsiella michiganensis M5al)
MHKFSLSLFTLSLGVALMPLAHAATTPVQEHLLEQVRLGEASKREDLVRQSLYRLELIDP
NNPDVVAARMRYLLRQGDTAGAKQQLERLAKLAPESPELKASRDEMKSSAGDGRQELQQA
RLLGVAGKVDEAIVAYEKLFNGVPDDDDAAIEYWTLVARLPARHNEGINQLKKLNARLPG
NVSLQTALAKQMFGDNKPEEGFAYLEQMSRSAAGRGIAADIWFNEVKSMPVSRASVQALQ
RFLMQFPTGSTSANARVLLAQQQTQLKDPTFRDRAEGLAAVKAGKGSVAVADLQQAVRAD
AKDSDAVGALGQAYSQRGDRARAVAQLSKAIKMDPDSPSRDKWDSLLKTNRYWLLIKQGD
SALKSGRLAQAQNHYAQAQRIDNTDSYAVLGLGDVAAARKENAAAERYYQRALRMDRGNS
LAVRGLANLYRGESPEKASAYIASLSPGQRRSIDDIERSLTNDRLEKQAEALESQGNWAQ
AAEVQRRRLALDPDSVWIAYRLSRDLVSAGSRSEADAIMRAMVNRQPGDADRVYAYGLYL
SGNNQDERALAQINALPRGQWTDNIRELEARLQSDNVLRQANQLRDDGQEDRAIALIQQQ
PASVRYALTLADWAQQRGDSQTAIAQYQRVLGQQPDNGDARLGLAEVYLADGDKNAARAQ
VAQLKGEDIDSINMQRRIAQAQAGLGDRAQAQQTFARIVPQAKAQPPSMESALVLRDAAR
FQAQNDEPQQALEGYKDAMVASGVARERPQDNDTFTRLTRNDSSDDWLKRGIRSDAADLY
RQQDLNVTLEHDYWGSSGTGGYSDLKAHTTMLHVDAPLADGRMFFRTDLVNMNAGSFSTK
SDGSYSPSWGTCGEIACTGGSKHQSDSGASVAVGWKNETWSGDIGTTPMGFNVVDVVGGL
SYSSDVGPLGYTVNLHRRPISSSLLAFGGQKDNPNDGHTGKSWGGVRADGGGVSLSYDKG
EANGVWSSLGVDQLTGKNVADNWRVRWMTGYYYKVVNEDNRRVTVGLNNMLWHYDKDLSG
YTLGQGGYYSPQEYVSFSVPVTWRQRTENWSWELGGSVSWSHSRTKTEARYPLLNLLPSQ
YRHDASQLTEEGSSSSGVGYTARALIERRVTSNWFVGAAVDIQQAKDYTPSHALLYVRYS
ASGWQGDMDMPPQPLVPYADW