Protein Info for BWI76_RS26200 in Klebsiella michiganensis M5al

Annotation: starch synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 477 TIGR02095: glycogen/starch synthase, ADP-glucose type" amino acids 1 to 476 (476 residues), 575.8 bits, see alignment E=3.5e-177 PF08323: Glyco_transf_5" amino acids 2 to 234 (233 residues), 247.7 bits, see alignment E=3.5e-77 PF13439: Glyco_transf_4" amino acids 128 to 221 (94 residues), 37.4 bits, see alignment E=6.6e-13 PF00534: Glycos_transf_1" amino acids 287 to 437 (151 residues), 48.6 bits, see alignment E=1.7e-16 PF13692: Glyco_trans_1_4" amino acids 293 to 437 (145 residues), 31.6 bits, see alignment E=4.9e-11

Best Hits

Swiss-Prot: 96% identical to GLGA_KLEP3: Glycogen synthase (glgA) from Klebsiella pneumoniae (strain 342)

KEGG orthology group: K00703, starch synthase [EC: 2.4.1.21] (inferred from 95% identity to kpu:KP1_5128)

MetaCyc: 91% identical to glycogen synthase (Escherichia coli K-12 substr. MG1655)
Starch synthase. [EC: 2.4.1.21]

Predicted SEED Role

"Glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21)" in subsystem Glycogen metabolism (EC 2.4.1.21)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.4.1.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285BB67 at UniProt or InterPro

Protein Sequence (477 amino acids)

>BWI76_RS26200 starch synthase (Klebsiella michiganensis M5al)
MQVLHVCSEMFPLLKTGGLADVIGALPAAQIAGGVDTRVLLPAFPDLRRGVTDAQVVTRR
ETFAGRITLLFGHFNGVGIYLIDAPHLYDRPGSPYHDTNQHAYTDNVLRFALLGWVGSEM
ACGLDPFWRPDVVHAHDWHAGLTPAYLAARGHPAKSVFTVHNLAYQGMFYSWHMNDIELP
WSFYNVHGLEFNGQISFLKAGLYYADHITAVSPTYAREITEPQFAYGMEGLLRQRQHEGR
LSGILNGVDDHIWNPESDLLLAARYDRDRLEEKAENKRQLQIAMGLKVDDKAPLFAVVSR
LTSQKGLDLVLEALPGLLEQGGQLALLGAGDPVLQEGFLAAAAEHPGKVGVQIGYHEAFS
HRIMGGADVILVPSRFEPCGLTQLYGLKYGTLPLVRRTGGLADTVSDCSLENLADGLATG
FVFEDSNALSLLRAIRRTFVLWSRPSLWRYVQRQAMNMDFSWQVAANSYRELYQRLL