Protein Info for BWI76_RS25060 in Klebsiella michiganensis M5al

Annotation: lipoprotein NlpI

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 294 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF13181: TPR_8" amino acids 62 to 94 (33 residues), 15.4 bits, see alignment 6e-06 PF13432: TPR_16" amino acids 67 to 128 (62 residues), 28.1 bits, see alignment E=8.2e-10 PF07719: TPR_2" amino acids 96 to 129 (34 residues), 23.1 bits, see alignment 1.9e-08

Best Hits

Swiss-Prot: 93% identical to NLPI_ECOLU: Lipoprotein NlpI (nlpI) from Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)

KEGG orthology group: K05803, lipoprotein NlpI (inferred from 97% identity to kpu:KP1_4880)

Predicted SEED Role

"Lipoprotein nlpI precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285BA03 at UniProt or InterPro

Protein Sequence (294 amino acids)

>BWI76_RS25060 lipoprotein NlpI (Klebsiella michiganensis M5al)
MKPFLRWCFVATALTLAGCSNSAWRKDAVLAVPLQPTLQQEVILARMEQILASRALTDDE
RAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFD
SVLELDPTYNYAHLNRGIALYYGGRAKLAQDDLLAFYQDDPNDPFRSLWLYLAERQLDEK
QALEALRQRLDKSDKEQWGWNIVGFYLGDISEKELMTRLKADATDNTSLAEHLSETNFYL
GKYYLSLGDKDSATALFKLAVANNVHNYVEHRYALLELSLLGQEQDDLAESDQQ