Protein Info for BWI76_RS23730 in Klebsiella michiganensis M5al

Annotation: glycerate kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 391 TIGR00045: glycerate kinase" amino acids 2 to 377 (376 residues), 430.1 bits, see alignment E=3.6e-133 PF02595: Gly_kinase" amino acids 3 to 377 (375 residues), 433.4 bits, see alignment E=3.5e-134

Best Hits

KEGG orthology group: None (inferred from 91% identity to kpn:KPN_01689)

Predicted SEED Role

"Glycerate kinase (EC 2.7.1.31)" in subsystem Allantoin Utilization or D-galactarate, D-glucarate and D-glycerate catabolism or Glycerolipid and Glycerophospholipid Metabolism in Bacteria or Glycine and Serine Utilization or Photorespiration (oxidative C2 cycle) or Serine-glyoxylate cycle (EC 2.7.1.31)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.31

Use Curated BLAST to search for 2.7.1.31

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B924 at UniProt or InterPro

Protein Sequence (391 amino acids)

>BWI76_RS23730 glycerate kinase (Klebsiella michiganensis M5al)
MKIVIALDSFKGSCSAQAACAAVARGLRRVDEALELVEMPVSDGGEGLLSTLAESPQLKG
ARWQQQRCTSPYGLAVQAAFLILPGERAIIEMAQSCGLELTPKAQRDVRLASSFGLGEQV
KAALDAGCRRLIIGLGGSATNDGGIGFAQALGARFLRKDGTLLPVPAAGQDLAHIQRIDL
SELDPRLRQAEIQASCDVTNPLLGTDGATWVYGAQKGADEAALSELEAGMAHYSRQLTQT
LGYDVSEAPGAGAAGGMGAALIAYAGGTLRPGIDLVLELLNADRHLSDAALTIVGEGWLD
RQSAFGKAPVGVAGKAARHGVPVVALCGGRDESSRQLYQHHIDAMWSICQRPMPLAESMN
TCEQLLADAAENVLRTFLSGRRGEAHKRITV