Protein Info for BWI76_RS23240 in Klebsiella michiganensis M5al

Annotation: exonuclease V subunit gamma

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1124 TIGR01450: exodeoxyribonuclease V, gamma subunit" amino acids 2 to 1086 (1085 residues), 1429.8 bits, see alignment E=0 PF04257: Exonuc_V_gamma" amino acids 2 to 345 (344 residues), 376.5 bits, see alignment E=1.1e-116 PF17946: RecC_C" amino acids 833 to 1048 (216 residues), 219.7 bits, see alignment E=3.7e-69

Best Hits

Swiss-Prot: 80% identical to RECC_ECOLI: RecBCD enzyme subunit RecC (recC) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 93% identity to eae:EAE_02110)

MetaCyc: 80% identical to exodeoxyribonuclease V subunit RecC (Escherichia coli K-12 substr. MG1655)
Exodeoxyribonuclease V. [EC: 3.1.11.5]; RXN-19004 [EC: 3.1.11.5]

Predicted SEED Role

"Exodeoxyribonuclease V gamma chain (EC 3.1.11.5)" in subsystem DNA-replication (EC 3.1.11.5)

Isozymes

Compare fitness of predicted isozymes for: 3.1.11.5

Use Curated BLAST to search for 3.1.11.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B7Q4 at UniProt or InterPro

Protein Sequence (1124 amino acids)

>BWI76_RS23240 exonuclease V subunit gamma (Klebsiella michiganensis M5al)
MLRVYHSNRLDVLEALMEFIVERQRLDDPFMPEMVLVQSTGMAQWLQMTLAQRFGIAANI
EFPLPASFIWDMFVRVLKDIPGESAFSKQSMSWKLMTLLPQRLDDESFTLLRHYLHDDSD
KRKLFQLAARVADLYDQYLVYRPEWLMRWEADQRVDGLGDAQEWQAPLWKALVEYTAELG
QPLWHRANLYQRFISALEAAEEPPAGLPSRVFICGISALPPVYLQALQALGKHVDVYVLF
TNPCRYYWGDIKDPAFLAKLLSRQRRHHRETTRALPLFRDTEQAPGLFNDAGEQDVGNPL
LASWGKLGRDYIYLLAGLERYEELDAFVDIAPDNLLHNLQADILELRNAAVAGRSAEEFA
NSGSKRLLAADDRSLTIHVCHSPQREVEVLHDRLLAMLEENPELTPRDIIVMVADIDSYS
PYIQAVFGSASGERWLPWAISDRRARESHPALQAFITLLSLPDSRFASEDVLALLDVPVL
AARFNIDEEGLRYLRQWVNESGVRWGMDDDNVRELDLPATGQHTWRFGLTRMLLGYAMDS
SEGEWRSVLPYDESSGLIAELVGNLASLLMQLNLWRRGLAQDRPLAEWLPVCRDLLNDFF
LPDSETEAALALIEQQWQAVIDGGVDAQYGETVPLSLLRDELSQRLDQQRISQRFLAGPV
NICTLMPMRSIPFKVVCLLGMNDGVYPRTLAPLGFDLMSQKPQRGDRSRRDDDRYLFLEA
LMSAEQKLYISYIGRSIQDNSERYPSVLVQELADYIGQSHCLEGDEELDCDASERRVKEH
ITHLHTRMPFDAANFLANEDQSYAREWLAAASQQGEAHGAFIQPLPTPDIDHLPFEQLLR
FWQHPVRAFFQQRLRVNFRSEESEIPDDEPFILEGLSRYQLNQQLLNTLIEEQDASVMYR
RFRAAGELPYGAFGELAWETQRQEMQNLAERVIACRQPGQSMEIDLQCNGVNITGWLQQV
QSDGLLRWRPSLLSVAQGMQLWLEHLVYCASGGTGESRLFVRKEGEWRFPPLAQEQAQGY
LNDLVDGYLQGMSKPLLLLPESGGAWLKVCYDAEKDVMLMDEETQQKARSKFLQAYEGNM
VVSGEGADVWYQRLWRTLEPEYYEEILTQTQRYLLPVFRFHQSE