Protein Info for BWI76_RS21700 in Klebsiella michiganensis M5al

Annotation: AraC family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 264 PF02311: AraC_binding" amino acids 38 to 105 (68 residues), 30.2 bits, see alignment E=5e-11 PF12833: HTH_18" amino acids 184 to 260 (77 residues), 75.1 bits, see alignment E=6.7e-25 PF00165: HTH_AraC" amino acids 221 to 260 (40 residues), 30 bits, see alignment 6.8e-11

Best Hits

Swiss-Prot: 54% identical to NIMR_ECOLI: HTH-type transcriptional regulator NimR (nimR) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to kpe:KPK_B0062)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (264 amino acids)

>BWI76_RS21700 AraC family transcriptional regulator (Klebsiella michiganensis M5al)
MPVNKKPVTSPEEFNADDFSQAAIALHVSSSGEYAGQRPHAHRKGQLILSMRGAVRCEVD
DALWLVPPGHAVWVPGEIPHRCRITKNADTCFLFIEPGAAAMPEICCTIAVTPLVRELVL
YLAEQEHTYSPDSKTARLAAVLLEHIPDVPVEALHLPVSDHPKIRIMAEALFNEPDDRRT
LKQWAAHLAISERSLARLIKEATGMSFGRWRQQLHLMIALSHLSEGQPVQRVAGTLGYDS
VSAFITMFRKALGKSPTQYFSSLD