Protein Info for BWI76_RS21680 in Klebsiella michiganensis M5al

Annotation: antitoxin of the YeeV-YeeU toxin-antitoxin system

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 119 PF06154: CbeA_antitoxin" amino acids 16 to 114 (99 residues), 156.6 bits, see alignment E=1.2e-50

Best Hits

Swiss-Prot: 62% identical to CBEA_ECOLI: Cytoskeleton bundling-enhancing antitoxin CbeA (cbeA) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 68% identity to seg:SG0267)

Predicted SEED Role

"YafW protein (antitoxin to YkfI)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (119 amino acids)

>BWI76_RS21680 antitoxin of the YeeV-YeeU toxin-antitoxin system (Klebsiella michiganensis M5al)
MQKATRVINHNIAEPWRGLRRNITPCFGARLVQEGNHLHYLADRASIAGTFNEADLRYLD
QAFPVLMKQMELMLASSELTPHIQRCITLHAKGLICEADTLGSCGYLFIVIYPTSAISA