Protein Info for BWI76_RS21340 in Klebsiella michiganensis M5al

Annotation: SoxR reducing system protein RseC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 159 transmembrane" amino acids 74 to 98 (25 residues), see Phobius details amino acids 104 to 124 (21 residues), see Phobius details PF04246: RseC_MucC" amino acids 8 to 139 (132 residues), 113.1 bits, see alignment E=4.5e-37

Best Hits

Swiss-Prot: 76% identical to RSEC_ECOLI: Protein RseC (rseC) from Escherichia coli (strain K12)

KEGG orthology group: K03803, sigma-E factor negative regulatory protein RseC (inferred from 89% identity to kva:Kvar_1168)

Predicted SEED Role

"Sigma factor RpoE regulatory protein RseC" in subsystem Transcription initiation, bacterial sigma factors

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B862 at UniProt or InterPro

Protein Sequence (159 amino acids)

>BWI76_RS21340 SoxR reducing system protein RseC (Klebsiella michiganensis M5al)
MIKEWATVVSWNNGIALVHCDVKASCSSCASRAGCGSRVLNKLGPQTSHTISVPCEQPLS
VGQKVELGIAESSLLGSAVLVYMAPLVGLFVMASIFQVLFANDFASLCGAILGGVGGFLV
ARGLSPGLASRQSWQPVIISVGLPPDLVRIETPSSQLGQ