Protein Info for BWI76_RS19885 in Klebsiella michiganensis M5al

Annotation: multidrug ABC transporter permease/ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 547 transmembrane" amino acids 12 to 37 (26 residues), see Phobius details amino acids 55 to 80 (26 residues), see Phobius details amino acids 125 to 144 (20 residues), see Phobius details amino acids 150 to 171 (22 residues), see Phobius details amino acids 234 to 254 (21 residues), see Phobius details amino acids 272 to 293 (22 residues), see Phobius details TIGR01194: cyclic peptide transporter" amino acids 2 to 527 (526 residues), 370.2 bits, see alignment E=9.1e-115 PF00005: ABC_tran" amino acids 341 to 477 (137 residues), 97.6 bits, see alignment E=4.8e-32

Best Hits

Swiss-Prot: 85% identical to YOJI_ECOLI: ABC transporter ATP-binding/permease protein YojI (yojI) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 91% identity to eae:EAE_24185)

Predicted SEED Role

"Type I secretion system ATPase, LssB family LapB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B6Y1 at UniProt or InterPro

Protein Sequence (547 amino acids)

>BWI76_RS19885 multidrug ABC transporter permease/ATP-binding protein (Klebsiella michiganensis M5al)
MELLLLVWRQYRWPFISVIALSLLSAALGIGLIAFINLRLITLVDTSLTVLPEFLGLLLL
LMAVTLGSQLALTTLGHHFVYRLRGEFIKRILDTQIEKIEKIGSASLLAGLTSDIRNITI
AFVRLPELVQGIILTFGSAAYLAWLSGKMMLVTALWLALTIWGGFILVSRVYKHMASLRE
SEDKLYHDYQTVLEGRKELTLNRERAEYVFNQLYLPDAQEYRHHIVRADTFHLSAVNWSN
IMMLGAIGLVFWMANSLGWANTAVAATYSLTLLFLRTPLLSAVGALPTLLSAQVAFNKLN
KFSLAPYRAEFPQPQAHPHWQTLELRDITFHYPDNTFAVGPINMTLKRGELVFLIGGNGS
GKSTLAMLLTGLYQPVSGQILLDGQPIAADKPEDYRKLFSAVFTDVWLFDRLLGPEGKAA
DPALVEKWLGYLQMNHKLRLDDGKILDLKLSKGQKKRVALLLALAEDRDIIMLDEWAADQ
DPHFRREFYQVLLPLMKEMGKTLFAISHDDHYFQHADRLLEMRGGQLSELSGKERELATR
DAVARTA