Protein Info for BWI76_RS18915 in Klebsiella michiganensis M5al

Annotation: NAD(P)-dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 274 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF01370: Epimerase" amino acids 8 to 213 (206 residues), 38.5 bits, see alignment E=4.5e-14

Best Hits

Swiss-Prot: 82% identical to YEEZ_ECO57: Protein YeeZ (yeeZ) from Escherichia coli O157:H7

KEGG orthology group: None (inferred from 90% identity to kpu:KP1_3678)

Predicted SEED Role

"Nucleoside-diphosphate-sugar epimerases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B6E9 at UniProt or InterPro

Protein Sequence (274 amino acids)

>BWI76_RS18915 NAD(P)-dependent oxidoreductase (Klebsiella michiganensis M5al)
MKKVAIVGLGWLGMPLALSLMSRGWQVTGSKTTEDGVEAARMCGIDSYPLRLEPQLVCDT
EDLDTLMNVDALVITLPARRTGPGEDFYLQAVQEIVDTALAHHVPRIIFTSSTSVYGNAS
GTLKENSPRNPQTASGRVLKELEDWLHNLPGTSVDILRLAGLVGPSRHPGRFFAGKSAPD
GQHGVNLVHLQDVIAAIELLLQAPKGGRIYNICAPKHPARGVFYPQMARELGLPVPVFSD
NPENGSGKIVDGSRICNELGFEYQYPDPLVMPME