Protein Info for BWI76_RS18135 in Klebsiella michiganensis M5al
Annotation: zinc ABC transporter ATP-binding protein ZnuC
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 89% identical to ZNUC_SHISS: Zinc import ATP-binding protein ZnuC (znuC) from Shigella sonnei (strain Ss046)
KEGG orthology group: K09817, zinc transport system ATP-binding protein [EC: 3.6.3.-] (inferred from 93% identity to kpe:KPK_1911)MetaCyc: 89% identical to Zn2+ ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-63-RXN [EC: 7.2.2.20]
Predicted SEED Role
"Zinc ABC transporter, ATP-binding protein ZnuC" in subsystem Transport of Zinc
Isozymes
Compare fitness of predicted isozymes for: 3.6.3.-
Use Curated BLAST to search for 3.6.3.- or 7.2.2.20
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A285B5W9 at UniProt or InterPro
Protein Sequence (250 amino acids)
>BWI76_RS18135 zinc ABC transporter ATP-binding protein ZnuC (Klebsiella michiganensis M5al) MTNLVTLENVAVVYGQRRVLSDISLTLKPGKILTLLGPNGAGKSTLVRVVLGLVAPTEGV IKREGHLRIGYVPQKLHLDATMPLTVSRFMLLRPGTHKRDILPALKRVQAGHLIDAPMQK LSGGETQRVLLARALLNQPQLLVLDEPTQGVDVNGQVALYDLINQLRQELNCAVLMVSHD LHLVMAKTDEVLCLNQHICCSGAPEVVSMHPEFISMFGQRGAEQLGIYRHHHNHRHDLQG RIVLRRGNDR