Protein Info for BWI76_RS17980 in Klebsiella michiganensis M5al

Annotation: RNA chaperone ProQ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 227 PF04352: ProQ" amino acids 8 to 115 (108 residues), 138.6 bits, see alignment E=7.8e-45 PF17516: ProQ_C" amino acids 179 to 227 (49 residues), 81.2 bits, see alignment 2.9e-27

Best Hits

Swiss-Prot: 90% identical to PROQ_KLEP3: RNA chaperone ProQ (proQ) from Klebsiella pneumoniae (strain 342)

KEGG orthology group: None (inferred from 92% identity to eae:EAE_22680)

Predicted SEED Role

"ProQ: influences osmotic activation of compatible solute ProP" in subsystem Proline, 4-hydroxyproline uptake and utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B5U7 at UniProt or InterPro

Protein Sequence (227 amino acids)

>BWI76_RS17980 RNA chaperone ProQ (Klebsiella michiganensis M5al)
MENQPKLNSSKEVIAFLAERFPQCFSAEGEARPLKVGIFQDLVERVGGEMNLSKTQLRAA
LRLYTSSWRYLYGVKPGAVRVDLDGNPCGELEEQHVAHARQQLEEAKARVQAQREAQQAK
KREAAAAAGQPEEGARRERKPRPQAQARRKEGAEQRKPRPAPAAKAPREERHTPVSDVSV
LTVGQALKVKAGNNAMDATVLEITKDGVRVQLTSGMSMIVRAEHLVF