Protein Info for BWI76_RS16525 in Klebsiella michiganensis M5al

Annotation: cyclopropane-fatty-acyl-phospholipid synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 383 PF02353: CMAS" amino acids 109 to 369 (261 residues), 349.6 bits, see alignment E=6.2e-108 PF01728: FtsJ" amino acids 156 to 225 (70 residues), 27.5 bits, see alignment E=1.4e-09 PF05175: MTS" amino acids 159 to 236 (78 residues), 24.5 bits, see alignment E=9.5e-09 PF13489: Methyltransf_23" amino acids 160 to 290 (131 residues), 51.6 bits, see alignment E=4.8e-17 PF01135: PCMT" amino acids 160 to 216 (57 residues), 21.9 bits, see alignment E=6.8e-08 PF13847: Methyltransf_31" amino acids 167 to 272 (106 residues), 44.3 bits, see alignment E=7.6e-15 PF13649: Methyltransf_25" amino acids 172 to 262 (91 residues), 63.6 bits, see alignment E=1.2e-20 PF08241: Methyltransf_11" amino acids 173 to 265 (93 residues), 54.3 bits, see alignment E=8.9e-18 PF08242: Methyltransf_12" amino acids 173 to 264 (92 residues), 40.1 bits, see alignment E=2.5e-13

Best Hits

Swiss-Prot: 86% identical to CFA_ECOLI: Cyclopropane-fatty-acyl-phospholipid synthase (cfa) from Escherichia coli (strain K12)

KEGG orthology group: K00574, cyclopropane-fatty-acyl-phospholipid synthase [EC: 2.1.1.79] (inferred from 92% identity to kpe:KPK_2348)

MetaCyc: 86% identical to cyclopropane fatty acyl phospholipid synthase (Escherichia coli K-12 substr. MG1655)
Cyclopropane-fatty-acyl-phospholipid synthase. [EC: 2.1.1.79]

Predicted SEED Role

"Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79)" (EC 2.1.1.79)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.79

Use Curated BLAST to search for 2.1.1.79

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B4X8 at UniProt or InterPro

Protein Sequence (383 amino acids)

>BWI76_RS16525 cyclopropane-fatty-acyl-phospholipid synthase (Klebsiella michiganensis M5al)
MSSSCIEEVVSVPNDDWYRIAAELLGRAGIEINGPAPSDLRIKNPLFFKRVLQEGSLGLG
ESYMDGWWDCERLDIFFHKVLRAGLENQLPHHFKDTLRIASARLFNLQSKKRSWIVGKEH
YDLGNDLFSRMLDPYMQYSCAYWKDAETLDDAQQAKLDLICRKLELEPGMRVLDIGCGWG
GLAYYMAKNYQVSVVGVTISAEQQKMAQERCADLDVTILLQDYRDLHESFDRIVSVGMFE
HVGPKNYATYFDVVDRNLKPDGRFLLHTIGSKKTDHSVDPWINKYIFPNGCLPSVRHIAE
ASESHFVMEDWHNFGADYDTTLMAWYERFLNSWPDIADNYSERFKRMFSYYLNACAGAFR
ARDIQLWQVVFSRGAEHGLRVAR