Protein Info for BWI76_RS15110 in Klebsiella michiganensis M5al

Annotation: putative excinuclease ABC subunit A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 753 PF17755: UvrA_DNA-bind" amino acids 151 to 248 (98 residues), 24.1 bits, see alignment E=9.5e-09 PF00005: ABC_tran" amino acids 466 to 671 (206 residues), 39.1 bits, see alignment E=2.9e-13

Best Hits

KEGG orthology group: None (inferred from 56% identity to cbf:CLI_2874)

Predicted SEED Role

"Excinuclease ABC subunit A paralog of unknown function" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B446 at UniProt or InterPro

Protein Sequence (753 amino acids)

>BWI76_RS15110 putative excinuclease ABC subunit A (Klebsiella michiganensis M5al)
MNTHDAIKIIGARQNNLQDIDLEVPKNKITVFTGVSGSGKSSLVFGTIAAESQRQLNDTF
PPFIRHRLPHYGNPEVDDIENLSVAIIIDQKRIGGNARSTVGTASDIYTLLRLLFSRVGE
PFVGYSNVFSFNHPAGMCATCDGLGIASTIDIDQLIDSNLSLNAGAIRYPSFAPGSWRWK
RYVYSGLFDADKKIADYSKEERELLLYADNLTPEAPLAGWPKSAKFEGVITRFTRSYLKQ
ETKDTKTEEFQRVVSLQVCPSCQGMRLNEKILSCRIRGKNIGECATLPVTELKLFVEKLD
YPEVRPLLEALLERLDAMCAVGLGYLDLNRTTPSLSGGESQRLKMVRHLGSSLTGIVYII
DEPSTGLHPADIVKLNVLIGKLRDKGNTILMVEHDPDMIAIAEHVIDLGPGAGKQGGNIV
FEGDLSALKQSQTLTGRYFSSRAEINNRPRCAKGYISVRNATLHNLHNLSVDVPLSVMVA
VTGVAGSGKSSFVMGALAPQCPDAIVIDQKPIHTSIRSHIASWCGAFDTIRLLFAEKNHV
SASWFSANAKGACPECHGLGVIQTDLAFMDTVTLPCEACQGQRYSPQALKYRYQGKNIAE
VLSLSINDAGDFFLNEPQLRPIFRSLVEVGLGYLRLGESLNHLSGGECQRLKLASQLNHD
SDMYIFDEPTTGLHPSDVASLLKLFNRLVDRGNTVIIIEHNMELIAQADWIIDIGPYAGQ
EGGKLLFSGTPESMLACRHSLTAEWLRKHCLVE