Protein Info for BWI76_RS11565 in Klebsiella michiganensis M5al

Annotation: DeoR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 252 PF08220: HTH_DeoR" amino acids 6 to 61 (56 residues), 64.7 bits, see alignment E=5.1e-22 PF00455: DeoRC" amino acids 76 to 232 (157 residues), 162.2 bits, see alignment E=1e-51

Best Hits

Swiss-Prot: 88% identical to YDJF_ECOLI: Uncharacterized HTH-type transcriptional regulator YdjF (ydjF) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 90% identity to sei:SPC_2441)

Predicted SEED Role

"Putative HTH-type transcriptional regulator YdjF"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B2F9 at UniProt or InterPro

Protein Sequence (252 amino acids)

>BWI76_RS11565 DeoR family transcriptional regulator (Klebsiella michiganensis M5al)
MAAKDRIQAIKQMVANDKKVAVSNLSAIFQVTEETIRRDLEKLEDEGFLTRTYGGAVLNT
SALSDNVHFYKRAKSHFEEKQVIARNALPFIKNKTTMAADSSSTAMELLKLLKERNDLTL
LTNSAEAFHELAQSEINVVSTGGELNKNTLSLQGRITKEIISRYHVDIMVMSCKGLDMQS
GALDSNEAEAEIKKTMIRQATEVALLVDHSKFDRKAFVQLVDFSHINYLITNKAPGAQWI
AFCKENNIQLVY