Protein Info for BWI76_RS10525 in Klebsiella michiganensis M5al

Annotation: cytosine/purines uracil thiamine allantoin permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 495 transmembrane" amino acids 41 to 64 (24 residues), see Phobius details amino acids 69 to 90 (22 residues), see Phobius details amino acids 96 to 115 (20 residues), see Phobius details amino acids 124 to 144 (21 residues), see Phobius details amino acids 161 to 181 (21 residues), see Phobius details amino acids 193 to 211 (19 residues), see Phobius details amino acids 234 to 254 (21 residues), see Phobius details amino acids 275 to 296 (22 residues), see Phobius details amino acids 316 to 339 (24 residues), see Phobius details amino acids 354 to 374 (21 residues), see Phobius details amino acids 380 to 404 (25 residues), see Phobius details amino acids 434 to 454 (21 residues), see Phobius details amino acids 460 to 476 (17 residues), see Phobius details PF02133: Transp_cyt_pur" amino acids 32 to 465 (434 residues), 289.7 bits, see alignment E=2e-90

Best Hits

KEGG orthology group: K03457, nucleobase:cation symporter-1, NCS1 family (inferred from 91% identity to kpn:KPN_01790)

Predicted SEED Role

"Cytosine/purine/uracil/thiamine/allantoin permease family protein" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B1T8 at UniProt or InterPro

Protein Sequence (495 amino acids)

>BWI76_RS10525 cytosine/purines uracil thiamine allantoin permease (Klebsiella michiganensis M5al)
MPNQQNTHQVKAADPHAGYSPRLCNEDLAPTRDQNWSWYNIFSFWMSDVHSMGGYVVAAS
FFTLGLASWQVLLCLLVGICIVQLCANLVAKPSQMAGVPYAVICRQAFGVFGANIPAVIR
GLIAFAWYGIQTYLAANALMLVLLKFWPSLSTLTASSFLGLSHLGWLCFATMWLLQAMVF
WHGMNAIKRFIDIAGPAVYVVMLALAGWIVYKTGFDGISFTLASKSLSAGEQTWQMITAT
ALVVSYFSGPLLNFGDFSRYGKSMGEIRRGNRWGLPFNFLLFSIVTVVIVSGTQSLFGRM
ITDPIETVSRVGNDLAVAIGLLTMITATIGINIVANFVSPAFDFSNCSPQKISFRTGGMI
AAVGSILLTPWNLFNSPELIHYTLDVLGAFIGPLFGILIVDFYIIKRGKVSVNDLFDDTP
KGQYWYRNGFNPKAIAALIPSVAIGLVISFIPALHEVANFSWFIGVFLSGAAYRWIARDE
RVGATAGFSALAQKE