Protein Info for BWI76_RS10505 in Klebsiella michiganensis M5al

Annotation: putative guanine/xanthin permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 460 transmembrane" amino acids 21 to 47 (27 residues), see Phobius details amino acids 53 to 71 (19 residues), see Phobius details amino acids 79 to 103 (25 residues), see Phobius details amino acids 114 to 135 (22 residues), see Phobius details amino acids 143 to 164 (22 residues), see Phobius details amino acids 176 to 196 (21 residues), see Phobius details amino acids 205 to 225 (21 residues), see Phobius details amino acids 245 to 268 (24 residues), see Phobius details amino acids 332 to 350 (19 residues), see Phobius details amino acids 356 to 379 (24 residues), see Phobius details amino acids 391 to 410 (20 residues), see Phobius details amino acids 416 to 439 (24 residues), see Phobius details TIGR00801: uracil-xanthine permease" amino acids 18 to 438 (421 residues), 360.9 bits, see alignment E=9.4e-112 PF00860: Xan_ur_permease" amino acids 23 to 408 (386 residues), 288.6 bits, see alignment E=3.3e-90 TIGR03173: xanthine permease" amino acids 26 to 439 (414 residues), 438.5 bits, see alignment E=2.1e-135

Best Hits

KEGG orthology group: None (inferred from 87% identity to eae:EAE_19210)

Predicted SEED Role

"Xanthine permease" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B1X0 at UniProt or InterPro

Protein Sequence (460 amino acids)

>BWI76_RS10505 putative guanine/xanthin permease (Klebsiella michiganensis M5al)
MSDEKNGGLLYGLEQRIPPLPAFFSALQHVLAGLVGIITPPLIIGAALGLGEWLPYLISM
SLLASGIGTFLQSNRVWGIGAGMICMQGTSFAFLGVAIAGGMWAKGQGGTPQDIMAMLFG
VNFVAALVPCLVSRFIEPLKRIFTPVITGSVIALIGISLIKVSVINWCGGEQAKAFASMS
NIALGAGTLGTIVLLSCAKNRWLRLSSVVVGIAVGCAAAALSGSFQLKGVGDVWFRLPQL
FPFGFQFNSAIFMPIALVSLVCILEAVGDLTANCLISRQSIDDEAFRSRLKGGILADGIS
CMVAAMLCAFPNTTFAQNNGVIQMTGVASRYVGRYIGVILILLGLFPPFGEILRQIPAPV
LGGATMVMFGCVVAAGIRIITQKPLTRRDMLIVGLAFGFGLGIEAVPAFLTHFPPIVGNL
FGSAATSGGLVAIVLNLIIPEEKPAAAAATRSTDDRAESL