Protein Info for BWI76_RS09660 in Klebsiella michiganensis M5al

Annotation: DNA translocase FtsK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1372 transmembrane" amino acids 22 to 44 (23 residues), see Phobius details amino acids 75 to 98 (24 residues), see Phobius details amino acids 109 to 131 (23 residues), see Phobius details amino acids 137 to 158 (22 residues), see Phobius details amino acids 165 to 184 (20 residues), see Phobius details PF13491: FtsK_4TM" amino acids 20 to 191 (172 residues), 148.4 bits, see alignment E=3.3e-47 PF17854: FtsK_alpha" amino acids 883 to 983 (101 residues), 101.3 bits, see alignment 6.3e-33 PF01580: FtsK_SpoIIIE" amino acids 991 to 1204 (214 residues), 286.8 bits, see alignment E=2e-89 PF09397: FtsK_gamma" amino acids 1307 to 1367 (61 residues), 96.6 bits, see alignment (E = 1.1e-31)

Best Hits

Predicted SEED Role

"Cell division protein FtsK" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton or Bacterial RNA-metabolizing Zn-dependent hydrolases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B1K3 at UniProt or InterPro

Protein Sequence (1372 amino acids)

>BWI76_RS09660 DNA translocase FtsK (Klebsiella michiganensis M5al)
MSQEYTEDKEVKFTKLSSGRRLLEALLILCSLFAIWLMAALLSFNPSDPSWSQTAWHEPI
HNLGGTPGAWLADTLFFIFGVMAYTIPVIIIGGCWFAWRHQENDEYIDYFAVSLRLIGAL
ALILTSCGLAAINADDIWYFASGGVIGSLLSTTLQPLLHSSGGTIALLCIWAAGLTLFTG
WSWVSIAEKLGGAILSILTFASNRTRRDDTWVDEGEYEEDEEEYEDDESTKPQGSRRARI
LRSALARRQRLAEKFANPLGRKTDAALFSGKRMDDAEGEVQYSASGAPVAADDVLFSGSS
AARPANADDVLFSGASAARPGDFDPYDPLLNGHSIADPVALAAQDTAAPQAWSEPLPGYD
AQPVYQPAPAYPPQYASQPEQAPVQQPAYQPEPAYPPQQAYQPAQAPVQQPAYQPEAAYP
PQHAYQPEQAPVQPPAYQPEAAYPPQQAYQPAQAPVQPPAYQPEPAYPPQQAYQPAQAPV
QPPAYQPEPAYPPQQAYQPAQAPVQQPAYQPEPAYPPQQAPIQQPEPYVPASAVEPEPAE
EVKPQRPPMYYFEEVEEKRAREREQLAAWYQPIPEPVSPVATKPISPPPAPAADVAAVSA
LAAGVHQATGASAAAASVASSAAPLFSPASGGPRAQVKEGIGPKLPRPNRVRVPTRRELA
SYGIKLPSQRLAEERARQAEHQHYDDDALTDEEVAEFEQGELARQFAAAQNQRYGDSYAA
EEDNVDEDSAAEAELARQFAASQQQRYASEQPPGSHPFSAADYEFSPMKTLVDDTPSEPV
FTPMPEVQQPAPQPTQHSQPVQQPMPHQQMHQQPQSAQPQAYQPVQQQPVQHPQMPQQAP
GGYPQQQASQQQQPIPQPQESLIHPLLMRNGDSRPLQKPTTLLPSLDLLTPPPAEVEPID
TFALEQMARLVEARLADFRIKADVVNYSPGPVITRFELNLAPGVKAARISNLSRDLARSL
STAAVRVVEVIPGKPYVGLELPNKRRQTVYLREVLDNAKFRDNPSPLTVVLGKDIAGEPV
TADLAKMPHLLVAGTTGSGKSVGVNAMILSMLYKAQPEDVKFIMIDPKMLELSVYEGIPH
LLTEVVTDMKDAANALRWSVNEMERRYKLMSALGVRNLAGYNEKIAEAARMGRPIPDPYW
KPGDSMDATHPVLKKEPYIVVLVDEFADLMMTVGKKVEELIARLAQKARAAGIHLVLATQ
RPSVDVITGLIKANIPTRIAFTVSSKIDSRTILDQGGAESLLGMGDMLYSAPNSTIPVRV
HGAFVRDEEVHAVVQDWKARGRPQYVDGITSDSESEGGGGGYEGGEELDPLFDQAVNFVT
EKRKASISGVQRQFRIGYNRAARIIEQMEAQGIVSEQGHNGNREVLAPPPFE