Protein Info for BWI76_RS08795 in Klebsiella michiganensis M5al

Annotation: DNA-binding response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 223 PF00072: Response_reg" amino acids 3 to 113 (111 residues), 89.6 bits, see alignment E=1.5e-29

Best Hits

Swiss-Prot: 80% identical to BASR_ECOLI: Transcriptional regulatory protein BasR (basR) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 94% identity to eae:EAE_14480)

Predicted SEED Role

"Transcriptional regulatory protein basR/pmrA" in subsystem Lipid A modifications or Orphan regulatory proteins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B119 at UniProt or InterPro

Protein Sequence (223 amino acids)

>BWI76_RS08795 DNA-binding response regulator (Klebsiella michiganensis M5al)
MKILVIEDDALLLQGLILAMQSEGYVCDGVSTAHEAALSLASNHYSLVVLDLGLPDEDGL
HFLARMRREKFSQPVLILTARDTVDDRISGLDTGADDYLVKPFALEELNARIRALLRRHN
NQGDNELTVGNLRLNVTRRLVWLGEQSLDLTPKEYALLSRLMMKAGSPVHREILYNDIYS
WDNEPATNTLEVHIHNLRDKVGKSRIRTVRGFGYMLVDNAETE