Protein Info for BWI76_RS08485 in Klebsiella michiganensis M5al

Annotation: glutamate mutase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF13941: MutL
  • amino acids 4 to 456 (453 residues), 461.8 bits, E=1.2e-142
• TIGR01319: conserved hypothetical protein
  • amino acids 6 to 461 (456 residues), 784.1 bits, E=2.2e-240

Best Hits

KEGG orthology group: None (inferred from 93% identity to esc:Entcl_1734)

Predicted SEED Role

"METHYLASPARTATE MUTASE (EC 5.4.99.1)" (EC 5.4.99.1)

MetaCyc Pathways

• L-isoleucine biosynthesis III (5/7 steps found)
• L-glutamate degradation VI (to pyruvate) (2/4 steps found)
• L-glutamate degradation VIII (to propanoate) (7/11 steps found)
• L-glutamate degradation VII (to butanoate) (7/12 steps found)
• methylaspartate cycle (12/19 steps found)

KEGG Metabolic Maps

• C5-Branched dibasic acid metabolism

Isozymes

Compare fitness of predicted isozymes for: 5.4.99.1

Use Curated BLAST to search for 5.4.99.1

Sequence Analysis Tools

See A0A285B0Z7 at UniProt or InterPro

Protein Sequence (462 amino acids)

>BWI76_RS08485 glutamate mutase (Klebsiella michiganensis M5al)
MQTVSVDIGSTWTKAALFAQEGDELTLVNHVLTPTTTHHLAEGFFASLNQVLNVADARPL
LNRGDVTLKYSSSAKGGLAVAAMGLVPSITLESAKVTAHSAGAKIAQYYAYKLNRHDIQE
LEATPPDILLFTGGTDGGEESYGLANAHALAESKLDCAIIYAGNRDIQDEVQAILGHKDL
TTVDNILPDLDHPNPYAARKAICDVFLSRIVKGKGLDVIVAETGEEPMPTPWTVYELVKT
ISHYDSAWKEFMLIDMGGATTDVYSACANTLSPDTVLHGVPEPFVKRTVEGDLGMRVSAV
VVGESTRELVNAVFAHQPQRQEAFYRYLRHLVAQPDYLPVNEEEKYFDTVLAGLCVGYAS
ERHAGTKKQVCTCVGNVDLQMGRDLTTVSKVVGSGGWLSRASRFDIQSWLKYRELDDDGR
RILLPTRFDYYRDAKGLLPLLANVARLYPELAARTSIHCLTL