Protein Info for BWI76_RS07305 in Klebsiella michiganensis M5al

Annotation: sucrose operon repressor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 334 TIGR02417: D-fructose-responsive transcription factor" amino acids 7 to 333 (327 residues), 486.3 bits, see alignment E=2.3e-150 PF00356: LacI" amino acids 7 to 55 (49 residues), 69.2 bits, see alignment 4.1e-23 PF00532: Peripla_BP_1" amino acids 67 to 240 (174 residues), 36.4 bits, see alignment E=8.7e-13 PF13407: Peripla_BP_4" amino acids 69 to 315 (247 residues), 43.9 bits, see alignment E=4.5e-15 PF13377: Peripla_BP_3" amino acids 183 to 332 (150 residues), 48.2 bits, see alignment E=2.8e-16

Best Hits

Swiss-Prot: 95% identical to SCRR_KLEPN: Sucrose operon repressor (scrR) from Klebsiella pneumoniae

KEGG orthology group: K03484, LacI family transcriptional regulator, sucrose operon repressor (inferred from 95% identity to kpu:KP1_1428)

Predicted SEED Role

"Sucrose operon repressor ScrR, LacI family" in subsystem Sucrose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B070 at UniProt or InterPro

Protein Sequence (334 amino acids)

>BWI76_RS07305 sucrose operon repressor (Klebsiella michiganensis M5al)
MKTKRVTIKDIAELAGVSKATASLVLNGRGKELRVAQETRERVLAIAREQHYQPSIHARS
LRDNRSHTIGLVVPEITNYGFAVFSHELEMLCREAGVQLLISCTDENPGQESMVVNNMIA
RQVDGLIVASCMHADADYLKLSEQLPVVLFDRYPNESALPLVMTDSITPTAELIARIAPQ
HRDEFWFLGGQPRLSPSRDRLAGFTQGLAQAGIELRPEWVINGNYHPSSGYEMFAALCAR
LGRPPKALFTAACGLLEGVLRYMSQHHLLDSDIHLASFDDHYLYDSLSLRIDTVQQDNRQ
LAWHCYDLISQLIDGNTPEPLQRYLPATLQFRHR