Protein Info for BWI76_RS04415 in Klebsiella michiganensis M5al

Annotation: oxaloacetate decarboxylase subunit beta

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 433 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details amino acids 42 to 64 (23 residues), see Phobius details amino acids 124 to 148 (25 residues), see Phobius details amino acids 159 to 183 (25 residues), see Phobius details amino acids 218 to 245 (28 residues), see Phobius details amino acids 266 to 290 (25 residues), see Phobius details amino acids 312 to 331 (20 residues), see Phobius details amino acids 341 to 362 (22 residues), see Phobius details amino acids 410 to 431 (22 residues), see Phobius details TIGR01109: sodium ion-translocating decarboxylase, beta subunit" amino acids 19 to 425 (407 residues), 646.1 bits, see alignment E=6.6e-199 PF03977: OAD_beta" amino acids 20 to 429 (410 residues), 524.1 bits, see alignment E=8.3e-162

Best Hits

Swiss-Prot: 95% identical to OADB_KLEPN: Oxaloacetate decarboxylase beta chain (oadB) from Klebsiella pneumoniae

KEGG orthology group: K01572, oxaloacetate decarboxylase, beta subunit [EC: 4.1.1.3] (inferred from 96% identity to kpe:KPK_4719)

Predicted SEED Role

"Oxaloacetate decarboxylase beta chain (EC 4.1.1.3)" in subsystem Na+ translocating decarboxylases and related biotin-dependent enzymes or Pyruvate metabolism I: anaplerotic reactions, PEP (EC 4.1.1.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.1.1.3

Use Curated BLAST to search for 4.1.1.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285BAA9 at UniProt or InterPro

Protein Sequence (433 amino acids)

>BWI76_RS04415 oxaloacetate decarboxylase subunit beta (Klebsiella michiganensis M5al)
MESLNALIQGMGLMHLDIGQAIMLLVSLLLLWLAIAKKFEPLLLLPIGFGGLLSNIPEAG
LALTALESLLAHHDAGQLAVIAAKLNCLPDVHAIKEALALALPSVQGQMEQQAVDMGYSA
GVLAVFYKVAIGSGIAPLVIFMGVGAMTDFGPLLANPRTLLLGAAAQFGIFATVLGALTL
NYFGIISFTLPQAAAIGIIGGADGPTAIYLSGKLAPELLGAIAVAAYSYMALVPLIQPPI
MKALTTDKERKIRMVQLRTVSRREKILFPAVLLLLVALLLPDAAPLLGMFCFGNLMRESG
VVERLSDTVQNALINIVTIFLGLSVGAKLVADKFLQPQTLGILVLGVIAFCIGTAAGVLM
AKLLNLFSHNKINPLIGSAGVSAVPMAARVSNKVGLESDAQNFLLMHAMGPNVAGVIGSA
IAAGVMLKYVLAM