Protein Info for BWI76_RS03660 in Klebsiella michiganensis M5al

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 621 PF02384: N6_Mtase" amino acids 123 to 388 (266 residues), 147.9 bits, see alignment E=8.7e-47 PF05175: MTS" amino acids 150 to 280 (131 residues), 23.2 bits, see alignment E=9.7e-09 PF07669: Eco57I" amino acids 234 to 333 (100 residues), 25 bits, see alignment E=4.5e-09 PF01420: Methylase_S" amino acids 451 to 602 (152 residues), 61.5 bits, see alignment E=2.5e-20

Best Hits

Predicted SEED Role

"Type I restriction-modification system, DNA-methyltransferase subunit M (EC 2.1.1.72)" in subsystem Restriction-Modification System (EC 2.1.1.72)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.72

Use Curated BLAST to search for 2.1.1.72

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285AXW9 at UniProt or InterPro

Protein Sequence (621 amino acids)

>BWI76_RS03660 hypothetical protein (Klebsiella michiganensis M5al)
MKNKNILEIMLSIIKNEQNIINTEQAVKVISCLLIKKYLSLSQEGTINIQRCNSSHNNDI
IGCIEQIESIIRRSDRFHDHNNTTVLTDLSYHLEELDKFISTTNLKNALDDINSLSHFYN
LRDDYAKLLSRMSDESGSSGAYYTPTAICELLTHDIPSSPSDYIYDPACGTSGLLLSAVY
KIKNTYKNVNLKVFGKDLSSFSCLLSLCNILLNNIDNFSIECGNSIQCNNLDHKYNLIIS
NPPFGKIDTYNNYFAHKYLEYNFLEHIMLSLENNGNAVIILPNRFFSDEHHEAITLKKKL
LSDFNVTKIISLPAGVFLPYTAVKTSILFFSKNGPTKQILVHDASTQYKITKSNPFSISN
TQEIISSLSQNNNSQSTWLLNHDELQSNYNFLERPEFYRERLNFNTSLEDIDSLDNNLSN
FDDVLFSLKNDIKRLKDDLDQIRTSNTSIKYNLDDILIIKAGLLLQKNNFSEKGEVPVFG
GNGIIGYTNEAKEFGETIVIGKVGALCGNVRYCNGDIWVTNNSMVVKNRKDDVVYMPYLA
KLLNAMELRKLSSGTAQQYITVRHIKSIDIKLPSIEIQIKIDNLLHQIENKINSMIKLRD
KINSCSIHIMNDITCNLQIIK