Protein Info for BWI76_RS03270 in Klebsiella michiganensis M5al

Annotation: sugar ABC transporter ATP-binding protein CymD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 376 PF00005: ABC_tran" amino acids 21 to 162 (142 residues), 109.8 bits, see alignment E=2.5e-35 PF17912: OB_MalK" amino acids 241 to 296 (56 residues), 44.9 bits, see alignment 2.7e-15 PF08402: TOBE_2" amino acids 290 to 363 (74 residues), 34.3 bits, see alignment E=3e-12

Best Hits

KEGG orthology group: K10112, maltose/maltodextrin transport system ATP-binding protein (inferred from 76% identity to ecr:ECIAI1_1938)

Predicted SEED Role

"Maltose/maltodextrin transport ATP-binding protein MalK (EC 3.6.3.19)" in subsystem Maltose and Maltodextrin Utilization (EC 3.6.3.19)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.19

Use Curated BLAST to search for 3.6.3.19

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B8Q4 at UniProt or InterPro

Protein Sequence (376 amino acids)

>BWI76_RS03270 sugar ABC transporter ATP-binding protein CymD (Klebsiella michiganensis M5al)
MATVSLRKIEKRYENGFKAVHGIDLEIHDGEFMVFVGPSGCAKSTTLRMIAGLEDISGGE
IYIGNRKVNDLPPKDRGIAMVFQNYALYPHKTVFDNMAFGLKMQKRPKDEIKRRVEDAAE
KLEITELLYRKPKEMSGGQRQRVAVGRAIVRKPDVFLFDEPLSNLDAKLRVSMRMKIAQL
HRSLKEEGHPATMIYVTHDQTEALTLGDRICVLNHGNIMQVDTPTDLYNYPNNKFVASFI
GSPSINLIDTAIRKNNERLYVEIAPGVEILIPHSKQVLLEGYINKPVCFGIRPEHISLAS
DDDDLNTFEGVLTVVENMGSEKFLYFIVGGKELIARVDTQDINPFHIGKTLRFNLNTAFC
HVFDFYNENNLTNVRV