Protein Info for BWI76_RS02775 in Klebsiella michiganensis M5al

Annotation: outer membrane protein assembly factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 577 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF17243: POTRA_TamA_1" amino acids 26 to 100 (75 residues), 76.5 bits, see alignment E=2e-25 PF07244: POTRA" amino acids 189 to 252 (64 residues), 41.4 bits, see alignment E=2.9e-14 PF01103: Omp85" amino acids 279 to 574 (296 residues), 123.7 bits, see alignment E=1.9e-39

Best Hits

Swiss-Prot: 86% identical to TAMA_CITRI: Translocation and assembly module subunit TamA (tamA) from Citrobacter rodentium (strain ICC168)

KEGG orthology group: K07278, outer membrane protein (inferred from 95% identity to kpe:KPK_5048)

Predicted SEED Role

"Uncharacterized protein YtfM precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285AWW1 at UniProt or InterPro

Protein Sequence (577 amino acids)

>BWI76_RS02775 outer membrane protein assembly factor (Klebsiella michiganensis M5al)
MLQIRQLCITSLLLVSGVASAASVRLQVEGLSGELEKNVRAQLSTIQSDEVTPDRRFRAR
VDDAIREGLKALGYYEPTIDFDLRPPPARGRQVLIAKVTPGEPVRIGGTEVILRGGARTD
RDYLDLLKTRPAIGTVLNHSDYDGFKSSLTRVALRKGYFDSEFNKSQLGVSLDRHQAFWD
IDYNSGERYRFGPVTFEGSQIRDEYLQNLVPFKQGDYYTSQDLAELNRRLAATGWFSSVV
VAPQFEKSRQTKILPLQGVVSPRKENTVETGVGYSTDVGPRVKGTWRKPWMNSYGHSLTS
SLSLSAPEQQLDFSYKVPLLKSPLEQYYLMQGGFKRTDLNDTKADSTTLGVSRFWEMSSG
WQRALNLRWSLDHFTQANVTNTTMLIYPGVSVNRTRSRGGLMPTWGDSQRYSVDYSNTMW
GSDINFIVMQAQDVWIRTLYDRHRFVVRGNLGWIEADNFSKVPPDLRFFAGGDRSIRGYK
YKSISPKDDDGKLMGASKLATGSLEYQYNVSGKWWGAVFVDSGEAVSDIRESNFKTGAGL
GVRWQSPVGPIKLDIARPIGDKEEHGLQFYIGLGPEL