Protein Info for BWI76_RS02410 in Klebsiella michiganensis M5al

Annotation: EF-P beta-lysylation protein EpmB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 342 TIGR00238: KamA family protein" amino acids 3 to 328 (326 residues), 473.6 bits, see alignment E=3e-146 TIGR03821: EF-P beta-lysylation protein EpmB" amino acids 15 to 335 (321 residues), 518.2 bits, see alignment E=6.9e-160 PF13353: Fer4_12" amino acids 111 to 181 (71 residues), 25.6 bits, see alignment E=1.4e-09 PF04055: Radical_SAM" amino acids 118 to 263 (146 residues), 34.7 bits, see alignment E=2e-12

Best Hits

Swiss-Prot: 86% identical to EPMB_SALTY: L-lysine 2,3-aminomutase (epmB) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: None (inferred from 87% identity to cko:CKO_03688)

MetaCyc: 84% identical to lysine 2,3-aminomutase (Escherichia coli K-12 substr. MG1655)
5.4.3.-

Predicted SEED Role

"Lysyl-lysine 2,3-aminomutase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285AWN6 at UniProt or InterPro

Protein Sequence (342 amino acids)

>BWI76_RS02410 EF-P beta-lysylation protein EpmB (Klebsiella michiganensis M5al)
MAHIVTLNTPSREDWLTQLADVVTSPDELLHLLNVDADANLLAGRDARRLFALRVPRAFI
ARMEPGNPNDPLLRQVLTSREEFVNAPGFTTDPLEEQHSVVPGLLHKYSNRALLLVKGGC
AVNCRYCFRRHFPYAENQGNKRNWQMAMEYIASHPELDEIIFSGGDPLMAKDPELDWLLT
QLEAIPHIKRLRIHSRLPIVIPARITDTLIARISASSLQVLLVNHINHANEIDAAFRTAM
KSLRIAGVTLLNQSVLLRGVNDDARTLADLSNALFDAGVMPYYLHVLDRVQGAAHFMVSD
EEARKIMRELLTMVSGYLVPKLAREIGGEPSKTPLDLGLKQR